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The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Name: | BTB (POZ) domain containing 1 |
Synonyms: | BTBD1, BTB domain containing 1, BTB (POZ) domain containing 1, C15orf1, NS5ATP8 |
Target Sequences: | NM_025238 NP_079514.1 Q9H0C5 |
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