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BRIP1 / BACH1

BRCA1 interacting protein C-terminal helicase 1

DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. Acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination. Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1.

Gene Name: BRCA1 interacting protein C-terminal helicase 1
Synonyms: BRIP1, BRCA1-interacting protein 1, Fanconi anemia group J protein, FANCJ, Protein FACJ
Target Sequences: NM_032043 NP_114432.2 Q9BX63

Publications (5)

1
BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function. Cantor SB, Bell DW, Ganesan S, Kass EM, Drapkin R, Grossman S, Wahrer DC, Sgroi DC, Lane WS, Haber DA, Livingston DM. Cell. 2001 105:149-60. (WB, IP; Human) [PubMed:11301010]
2
Cardiomyocyte-specific knockout and agonist of peroxisome proliferator-activated receptor-gamma both induce cardiac hypertrophy in mice. Duan SZ, Ivashchenko CY, Russell MW, Milstone DS, Mortensen RM. Circulation research. 2005 97:372-9. (IHC, WB; Mouse) [PubMed:16051889]
3
Expression of the BRCA1-interacting protein Brip1/BACH1/FANCJ is driven by E2F and correlates with human breast cancer malignancy. Eelen G, Vanden Bempt I, Verlinden L, Drijkoningen M, Smeets A, Neven P, Christiaens MR, Marchal K, Bouillon R, Verstuyf A. Oncogene. 2008 27:4233-41. (IHC-P; Human) [PubMed:18345034]
4
CtIP- and ATR-dependent FANCJ phosphorylation in response to DNA strand breaks mediated by DNA replication. Sakasai R, Sakai A, Iimori M, Kiyonari S, Matsuoka K, Kakeji Y, Kitao H, Maehara Y. Genes to cells : devoted to molecular & cellular mechanisms. 2012 17:962-70. (WB; Human) [PubMed:23157317]
5
Genotyping of fanconi anemia patients by whole exome sequencing: advantages and challenges. Knies K, Schuster B, Ameziane N, Rooimans M, Bettecken T, de Winter J, Schindler D. PloS one. 2012 7:e52648. (WB; Human) [PubMed:23285130] [PMC:PMC3527584]
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Antibodies (36)
Primary (36)
BRIP1 / BACH1 (36)
Human (35)
Mouse (9)
Rat (3)
Chimpanzee (3)
Gibbon (3)
IHC (5)
IHC-P (3)
WB (31)
ELISA (13)
IF (7)
IP (9)
rabbit (25)
mouse (10)
chicken (1)
Product Group
IHCPlus (1)
IgG (19)
IgG1 (8)
IgG1,k (2)
IgY (1)
monoclonal mc (10)
polyclonal pc (26)
pp15-IB4 (1)
TS106 (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (20)
C-Terminus (7)
aa132-163 (6)
aa1100-1150 (1)
aa1200-C-term (1)
aa2-160 (1)
aa92-104 (1)
No (36)
BRIP1 / BACH1 Antibody - Anti-BRIP1 / FANCJ antibody IHC of human spleen, periarteriolar lymphoid sheath. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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BRIP1 / BACH1 Mouse anti-Human Monoclonal (pp15-IB4) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
0.1 ml/$460
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BRIP1 / BACH1 Rabbit anti-Human Polyclonal (aa92-104) Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$890
BRIP1 / BACH1 Antibody - Immunohistochemistry of paraffin-embedded Rat ovary using BACH1 Polyclonal Antibody at dilution of 1:100 (40x lens).
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BRIP1 / BACH1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
BRIP1 / BACH1 Antibody - Brip 1 detected in cell lysates. Lane 1: MCF-7 lysate, Lane 2: HeLa lysate, Lane 3:293 lysate and Lane 4: SKOV3 lysate.
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BRIP1 / BACH1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IP, WB
Unconjugated
100 µl/$386
BRIP1 / BACH1 Antibody - Western blot analysis of extracts of various cells.
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BRIP1 / BACH1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
BRIP1 / BACH1 Antibody - Immunohistochemistry of paraffin-embedded human testis tissue at dilution of 1:100
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BRIP1 / BACH1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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BRIP1 / BACH1 Mouse anti-Human Monoclonal (aa2-160) (TS106) Antibody
Human
IHC, WB
Unconjugated
100 µg/$884
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BRIP1 / BACH1 Rabbit anti-Human Polyclonal (aa132-163) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
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BRIP1 / BACH1 Rabbit anti-Human Polyclonal (aa132-163) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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BRIP1 / BACH1 Rabbit anti-Human Polyclonal (aa132-163) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
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BRIP1 / BACH1 Rabbit anti-Human Polyclonal (aa132-163) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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BRIP1 / BACH1 Rabbit anti-Human Polyclonal (aa132-163) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
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BRIP1 / BACH1 Rabbit anti-Human Polyclonal (aa132-163) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
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BRIP1 / BACH1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
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BRIP1 / BACH1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
Select
BRIP1 / BACH1 Rabbit anti-Human Polyclonal (aa1200-C-term) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
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BRIP1 / BACH1 Mouse anti-Human Monoclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µg/$748
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BRIP1 / BACH1 Mouse anti-Human Monoclonal (HRP) Antibody
Human
IF, IP, WB
HRP Conjugated
100 µl/$989
Select
BRIP1 / BACH1 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
IF, IP, WB
Biotin Conjugated
100 µl/$989
Select
BRIP1 / BACH1 Mouse anti-Human Monoclonal (FITC) Antibody
Human
IF, IP, WB
FITC Conjugated
100 µl/$989
Select
BRIP1 / BACH1 Mouse anti-Human Monoclonal (APC) Antibody
Human
IF, IP, WB
APC Conjugated
100 µl/$989
Select
BRIP1 / BACH1 Mouse anti-Human Monoclonal (PE) Antibody
Human
IF, IP, WB
PE Conjugated
100 µl/$989
Select
BRIP1 / BACH1 Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
100 µl/$649
Select
BRIP1 / BACH1 Mouse anti-Human Monoclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µg/$786
Select
BRIP1 / BACH1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$357
Viewing 1-25 of 36 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).