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BRIP1 / BACH1
BRCA1 interacting protein C-terminal helicase 1
DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. Acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination. Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1.
| Gene Name: | BRCA1 interacting protein C-terminal helicase 1 |
| Synonyms: | BRIP1, BRCA1-interacting protein 1, Fanconi anemia group J protein, FANCJ, Protein FACJ |
| Target Sequences: | NM_032043 NP_114432.2 Q9BX63 |
Publications (5)
1
BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function. Cantor SB, Bell DW, Ganesan S, Kass EM, Drapkin R, Grossman S, Wahrer DC, Sgroi DC, Lane WS, Haber DA, Livingston DM. Cell. 2001 105:149-60. (WB, IP; Human)
[PubMed:11301010]
2
Cardiomyocyte-specific knockout and agonist of peroxisome proliferator-activated receptor-gamma both induce cardiac hypertrophy in mice. Duan SZ, Ivashchenko CY, Russell MW, Milstone DS, Mortensen RM. Circulation research. 2005 97:372-9. (IHC, WB; Mouse)
[PubMed:16051889]
3
Expression of the BRCA1-interacting protein Brip1/BACH1/FANCJ is driven by E2F and correlates with human breast cancer malignancy. Eelen G, Vanden Bempt I, Verlinden L, Drijkoningen M, Smeets A, Neven P, Christiaens MR, Marchal K, Bouillon R, Verstuyf A. Oncogene. 2008 27:4233-41. (IHC-P; Human)
[PubMed:18345034]
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Antibodies
(36)
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Over-Expression Lysate
(2)
Primary
(36)
Target
BRIP1 / BACH1
(38)
Reactivity
Human
(35)
Mouse
(8)
Rat
(2)
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(3)
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(3)
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(4)
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(3)
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(31)
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(13)
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(10)
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rabbit
(25)
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(10)
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(1)
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(1)
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(19)
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(8)
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(2)
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(1)
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monoclonal mc
(10)
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(26)
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(1)
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(1)
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(2)
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(1)
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(4)
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(4)
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(4)
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(2)
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(20)
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(7)
aa132-163
(6)
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(1)
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(1)
aa2-160
(1)
aa92-104
(1)
Publications
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(38)
Tag
Myc-DDK (Flag)
(2)
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Human
(1)
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293T Cells
(1)
HEK 293 Cells
(1)
BRIP1 / BACH1 Mouse anti-Human Monoclonal (pp15-IB4) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
0.1 ml/$460
BRIP1 / BACH1 Rabbit anti-Human Polyclonal (aa92-104) Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$890
BRIP1 / BACH1 Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
BRIP1 / BACH1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IP, WB
Unconjugated
100 µl/$386
BRIP1 / BACH1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
BRIP1 / BACH1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
BRIP1 / BACH1 Mouse anti-Human Monoclonal (aa2-160) (TS106) Antibody
Human
IHC, WB
Unconjugated
100 µg/$884
BRIP1 / BACH1 Rabbit anti-Human Polyclonal (aa132-163) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
BRIP1 / BACH1 Rabbit anti-Human Polyclonal (aa132-163) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
BRIP1 / BACH1 Rabbit anti-Human Polyclonal (aa132-163) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
BRIP1 / BACH1 Rabbit anti-Human Polyclonal (aa132-163) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
BRIP1 / BACH1 Rabbit anti-Human Polyclonal (aa132-163) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
BRIP1 / BACH1 Rabbit anti-Human Polyclonal (aa132-163) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
BRIP1 / BACH1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
BRIP1 / BACH1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
BRIP1 / BACH1 Rabbit anti-Human Polyclonal (aa1200-C-term) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
BRIP1 / BACH1 Mouse anti-Human Monoclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µg/$748
BRIP1 / BACH1 Mouse anti-Human Monoclonal (HRP) Antibody
Human
IF, IP, WB
HRP Conjugated
100 µl/$989
BRIP1 / BACH1 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
IF, IP, WB
Biotin Conjugated
100 µl/$989
BRIP1 / BACH1 Mouse anti-Human Monoclonal (FITC) Antibody
Human
IF, IP, WB
FITC Conjugated
100 µl/$989
BRIP1 / BACH1 Mouse anti-Human Monoclonal (APC) Antibody
Human
IF, IP, WB
APC Conjugated
100 µl/$989
BRIP1 / BACH1 Mouse anti-Human Monoclonal (PE) Antibody
Human
IF, IP, WB
PE Conjugated
100 µl/$989
BRIP1 / BACH1 Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
100 µl/$649
BRIP1 / BACH1 Mouse anti-Human Monoclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µg/$786
BRIP1 / BACH1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$357
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of 38
product results
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