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BRD2 / RING3

bromodomain containing 2

BRD2 / RING3 is a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene.

Gene Name: bromodomain containing 2
Family/Subfamily: Protein Kinase , BRD
Synonyms: BRD2, Bromodomain containing 2, FSRG1, KIAA9001, NaT, RING3, RNF3, O27.1.1, Bromodomain-containing 2, D6S113E, FSH
Target Sequences: NM_005104 NP_005095.1 P25440

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Proteins (3)
Recombinant (3)
BRD2 / RING3 (3)
No (3)
GST (1)
His (1)
His, N-Terminal (1)
Human (3)
E. coli (2)
Wheat Germ Extract (1)
Purified (2)
BRD2 / RING3 Protein - 12.5% SDS-PAGE of human BRD2 stained with Coomassie Blue
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Wheat Germ Extract
GST
114.5 kDa
10 µg/$479; 25 µg/$670
BRD2 / RING3 Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
BRD2 / RING3 Protein - Recombinant Bromodomain Containing Protein 2 (BRD2) by SDS-PAGE
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E. coli
His, N-Terminal
30.6kDa
10 µg/$252; 50 µg/$315; 200 µg/$522; 100 µg/$417; 1 mg/$1,404; 500 µg/$1,034; 5 mg/$2,303; 2 mg/$1,565
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).