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BOK belongs to the BCL2 family, members of which form homo- or heterodimers, and act as anti- or proapoptotic regulators that are involved in a wide variety of cellular processes. Studies in rat show that this protein has restricted expression in reproductive tissues, interacts strongly with some antiapoptotic BCL2 proteins, not at all with proapoptotic BCL2 proteins, and induces apoptosis in transfected cells. Thus, this protein represents a proapoptotic member of the BCL2 family.
Gene Name: | BCL2-related ovarian killer |
Synonyms: | BOK, Bcl2-L-9, BCL2L9, BOKL, HBOK, Bcl-2-like protein 9, BCL2-related ovarian killer |
Target Sequences: | NM_032515 AAD51719.1 Q9UMX3 |
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