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BMP2K / BIKE
BMP2 inducible kinase
BMP2K / BIKE is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | BMP2 inducible kinase |
| Family/Subfamily: | Protein Kinase , NAK |
| Synonyms: | BMP2K, BMP2 inducible kinase, BIKE, BMP-2-inducible protein kinase, BMP-2 inducible kinase, HRIHFB2017, Bike kinase |
| Target Sequences: | NM_017593 NP_060063.2 Q9NSY1 |
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