Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.
Gene Name: | bone morphogenetic protein 10 |
Family/Subfamily: | TGF beta , not assigned-TGF beta |
Synonyms: | BMP10, BMP-10, Bone morphogenetic protein 10 |
Target Sequences: | NM_014482 NP_055297.1 O95393 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.