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BGN / Biglycan

biglycan

BGN / Biglycan is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. The encoded protein and decorin are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while this protein probably contains two chains. For this reason, this protein is called biglycan. This protein plays a role in assembly of collagen fibrils and muscle regeneration. It interacts with several proteins involved in muscular dystrophy, including alpha-dystroglycan, alpha- and gamma-sarcoglycan and collagen VI, and it is critical for the assembly of the dystrophin-associated protein complex.

Gene Name: biglycan
Synonyms: BGN, Bone/cartilage proteoglycan I, Biglycan, Biglycan proteoglycan, DSPG1, PG-S1, Small leucine-rich protein 1A, PGI, Bone/cartilage proteoglycan-I, SLRR1A
Target Sequences: NM_001711 NP_001702.1 P21810

Publications (2)

1
Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs. Nakamichi R, Ito Y, Inui M, Onizuka N, Kayama T, Kataoka K, Suzuki H, Mori M, Inagawa M, Ichinose S, Lotz MK, Sakai D, Masuda K, Ozaki T, Asahara H. Nature communications. 2016 7:12503. (IHC, WB, ELISA; Human) [Full Text Article] [PubMed:27527664] [PMC:PMC4990710]
2
Airn Regulates Igf2bp2 Translation in Cardiomyocytes. Hosen MR, Militello G, Weirick T, Ponomareva Y, Dassanayaka S, Moore JB 4th, Döring C, Wysoczynski M, Jones SP, Dimmeler S, Uchida S. Circulation research. 2018 May;122:1347-1353. [Full Text Article] [PubMed:29483092] [PMC:PMC5948151]

☰ Filters
Products
Antibodies (80)
Primary (80)
BGN / Biglycan (80)
Human (40)
Mouse (23)
Rat (39)
Bovine (4)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Guinea pig (3)
Hamster (4)
Horse (5)
Monkey (4)
Orangutan (3)
Pig (12)
Rabbit (3)
Sheep (4)
Zebrafish (1)
IHC (9)
IHC-P (6)
WB (74)
Flo (1)
ELISA (8)
ICC (8)
IF (1)
IP (9)
Peptide-ELISA (2)
rabbit (70)
mouse (9)
goat (1)
Product Group
IHCPlus (3)
IgG (25)
IgG2a,k (1)
monoclonal mc (9)
polyclonal pc (71)
4E1-1G7 (1)
APC (7)
APC Conjugated (8)
Biotin Conjugated (10)
Cy3 Conjugated (7)
Cy7 Conjugated (7)
FITC Conjugated (10)
HRP Conjugated (10)
PE Conjugated (8)
Preservative Free (1)
Unconjugated (20)
aa230-366 (16)
aa48-158 (16)
aa242-369 (8)
aa243-369 (8)
aa53-166 (8)
aa215-264 (4)
aa148-176 (1)
aa357-368 (1)
No (80)
BGN / Biglycan Antibody - Immunohistochemistry of monoclonal antibody to BGN on formalin-fixed paraffin-embedded human lung, adenosquamous cell carcinoma. [antibody concentration 1 ~ 10 ug/ml]
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BGN / Biglycan Mouse anti-Human Monoclonal (4E1-1G7) Antibody
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
100 µg/$423
BGN / Biglycan Antibody - Immunohistochemistry of paraffin-embedded Human gastric cancer using BGN Polyclonal Antibody at dilution of 1:50.
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BGN / Biglycan Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
BGN / Biglycan Antibody - Human Spleen, Trabecula: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BGN / Biglycan Rabbit anti-Mouse Polyclonal (aa53-166) Antibody
Mouse
IHC, IHC-P, WB
Unconjugated
100 µl/$460
BGN / Biglycan Antibody - Antibody (0.1 ug/ml) staining of Rat Skin lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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BGN / Biglycan Goat anti-Human Polyclonal (aa357-368) Antibody
Zebrafish, Pig, Horse, Rat, Hamster, Mouse, Dog, Sheep, Bovine, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
BGN / Biglycan Antibody - Formalin-fixed and paraffin-embedded human brain tissue reacted with BGN Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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BGN / Biglycan Rabbit anti-Human Polyclonal (aa148-176) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
BGN / Biglycan Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer using BGN Polyclonal Antibody at dilution of 1:50.
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BGN / Biglycan Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
BGN / Biglycan Antibody - Western blot of recombinant BGN / Biglycan.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BGN / Biglycan Rabbit anti-Mouse Polyclonal (aa242-369) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
BGN / Biglycan Antibody - Human Spleen, Trabecula: Formalin-Fixed, Paraffin-Embedded (FFPE)
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BGN / Biglycan Rabbit anti-Human Polyclonal (aa230-366) Antibody
Pig, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
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BGN / Biglycan Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
BGN / Biglycan Antibody - BGN / Biglycan antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BGN / Biglycan Rabbit anti-Human Polyclonal (aa215-264) Antibody
Horse, Human
WB
Unconjugated
100 µl/$424
BGN / Biglycan Antibody - Western blot analysis of extracts of various cell lines.
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BGN / Biglycan Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
BGN / Biglycan Antibody - Western blot of recombinant BGN / Biglycan.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BGN / Biglycan Rabbit anti-Mouse Polyclonal (aa53-166) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
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BGN / Biglycan Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
BGN / Biglycan Antibody - Human Spleen, Trabecula: Formalin-Fixed, Paraffin-Embedded (FFPE)
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BGN / Biglycan Rabbit anti-Human Polyclonal (aa230-366) Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
BGN / Biglycan Antibody - 1:100 staining human Melanoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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BGN / Biglycan Rabbit anti-Human Polyclonal Antibody
Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
BGN / Biglycan Antibody - Western blot of recombinant BGN / Biglycan.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BGN / Biglycan Mouse anti-Rat Monoclonal (aa48-158) Antibody
Rat
ICC, IP, WB
Unconjugated
100 µl/$323; 200 µl/$371; 500 µl/$531; 1 ml/$617
BGN / Biglycan Antibody - Western blot of recombinant BGN / Biglycan.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BGN / Biglycan Mouse anti-Rat Monoclonal (aa48-158) (HRP) Antibody
Rat
ICC, IP, WB
HRP Conjugated
100 µl/$356; 200 µl/$419; 500 µl/$642; 1 ml/$801
BGN / Biglycan Antibody - Western blot of recombinant BGN / Biglycan.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BGN / Biglycan Mouse anti-Rat Monoclonal (aa48-158) (Biotin) Antibody
Rat
ICC, IP, WB
Biotin Conjugated
100 µl/$334; 200 µl/$387; 500 µl/$563; 1 ml/$678
BGN / Biglycan Antibody - Western blot of recombinant BGN / Biglycan.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BGN / Biglycan Mouse anti-Rat Monoclonal (aa48-158) (FITC) Antibody
Rat
ICC, IP, WB
FITC Conjugated
100 µl/$367; 200 µl/$435; 500 µl/$691; 1 ml/$850
BGN / Biglycan Antibody - Western blot of recombinant BGN / Biglycan.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BGN / Biglycan Mouse anti-Rat Monoclonal (aa48-158) (APC) Antibody
Rat
ICC, IP, WB
APC Conjugated
100 µl/$435; 200 µl/$531; 500 µl/$942; 1 ml/$1,112
BGN / Biglycan Antibody - Western blot of recombinant BGN / Biglycan.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BGN / Biglycan Mouse anti-Rat Monoclonal (aa48-158) (PE) Antibody
Rat
ICC, IP, WB
PE Conjugated
100 µl/$435; 200 µl/$531; 500 µl/$942; 1 ml/$1,112
BGN / Biglycan Antibody - Western blot of recombinant BGN / Biglycan.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BGN / Biglycan Mouse anti-Rat Monoclonal (aa48-158) (APC, Cy7) Antibody
Rat
ICC, IP, WB
APC, Cy7 Conjugated
100 µl/$547; 200 µl/$740; 500 µl/$1,281; 1 ml/$1,601
BGN / Biglycan Antibody - Western blot of recombinant BGN / Biglycan.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BGN / Biglycan Mouse anti-Rat Monoclonal (aa48-158) (Cy3) Antibody
Rat
ICC, IP, WB
Cy3 Conjugated
100 µl/$435; 200 µl/$531; 500 µl/$942; 1 ml/$1,112
BGN / Biglycan Antibody - Immunocytochemistry analysis of human pancreatic cancer using BGN Antibody at dilution of 1:100
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BGN / Biglycan Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
BGN / Biglycan Antibody - Western blot analysis of extracts of various cell lines, using BGN antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 5s.
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BGN / Biglycan Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).