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Infectious Disease
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Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
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Customer Service: (800) 227-6666 / (650) 697-3600
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BDNF
brain-derived neurotrophic factor
During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
| Gene Name: | brain-derived neurotrophic factor |
| Family/Subfamily: | NGF Beta , not assigned-NGF Beta |
| Synonyms: | BDNF, ANON2, Abrineurin, BULN2, Neurotrophin |
| Target Sequences: | NM_001709 NP_001700.2 P23560 |
Publications (8)
1
Direct angiotensin AT2 receptor stimulation using a novel AT2 receptor agonist, compound 21, evokes neuroprotection in conscious hypertensive rats. McCarthy CA, Vinh A, Miller AA, Hallberg A, Alterman M, Callaway JK, Widdop RE. PloS one. 2014 9:e95762. (Flo; Rat)
[Full Text Article]
[PubMed:24752645]
[PMC:PMC3994132]
Related Antibodies: LS-B3815.
2
Antidepressant-Like Effects of Acupuncture-Insights From DNA Methylation and Histone Modifications of Brain-Derived Neurotrophic Factor. Jiang H, Zhang X, Lu J, Meng H, Sun Y, Yang X, Zhao B, Bao T. Frontiers in psychiatry. 2018 March;9:102. (Human)
[Full Text Article]
[PubMed:29636708]
[PMC:PMC5880910]
Related Antibodies: LS-C343943.
3
TRKB tyrosine kinase receptor is a potential therapeutic target for poorly differentiated oral squamous cell carcinoma. Moriwaki K, Ayani Y, Kuwabara H, Terada T, Kawata R, Asahi M. Oncotarget. 2018 May;9:25225-25243. (Human)
[Full Text Article]
[PubMed:29861866]
[PMC:PMC5982746]
☰ Filters
Products
Proteins
(64)
Type
Over-Expression Cell Culture Supernatant
(2)
Over-Expression Lysate
(34)
Recombinant
(28)
Target
BDNF
(64)
Format
Animal-free
(1)
Publications
No
(64)
Tag
GST
(3)
His
(7)
His, N-Terminal
(8)
His-GST
(2)
His-SUMO
(1)
Myc-DDK (Flag)
(33)
Species
Chicken
(1)
Dog
(1)
Guinea pig
(1)
Horse
(1)
Human
(37)
Mouse
(1)
Pig
(3)
Rabbit
(1)
Rat
(2)
Source
293F Cells
(1)
293T Cells
(16)
CHO Cells
(1)
E. coli
(22)
HEK 293 Cells
(21)
Wheat Germ Extract
(2)
Purification
Purified
(7)
Supernatant
(2)
Low Endotoxin Level
Low endotoxin level
(10)
Biologically Active
Biologically active
(6)
Animal-free
Animal-free
(1)
E. coli
His, N-Terminal
16.6 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
293F Cells
His, N-Terminal
25kDa
10 µg/$482; 50 µg/$1,156; 200 µg/$1,876; 100 µg/$1,623; 1 mg/$3,841; 500 µg/$2,728; 5 mg/$9,601
E. coli
His
13.5 kDa
10 µg/$304; 50 µg/$587; 100 µg/$940; 200 µg/$1,133; 1 mg/$2,340; 500 µg/$1,848; 5 mg/$4,103; 2 mg/$2,532
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
27.0 kDa
2 µg/$268; 10 µg/$349
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
2 µg/$281; 10 µg/$369
E. coli
His, N-Terminal
14.7 kDa
10 µg/$294; 50 µg/$522; 100 µg/$832; 200 µg/$1,034; 1 mg/$2,192; 500 µg/$1,712; 5 mg/$3,641; 2 mg/$2,383
E. coli
His-GST
45.0 kDa
50 µg/$482; 10 µg/$287; 200 µg/$962; 100 µg/$770; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
E. coli
His
15.2 kDa
10 µg/$300; 50 µg/$562; 100 µg/$897; 200 µg/$1,096; 1 mg/$2,284; 500 µg/$1,796; 5 mg/$3,921; 2 mg/$2,476
E. coli
His-GST
44.1 kDa
50 µg/$492; 10 µg/$289; 200 µg/$982; 100 µg/$785; 1 mg/$2,119; 500 µg/$1,646; 5 mg/$3,431; 2 mg/$2,309
E. coli
His
27.7 kDa
10 µg/$297; 50 µg/$542; 100 µg/$865; 200 µg/$1,065; 1 mg/$2,239; 500 µg/$1,755; 5 mg/$3,781; 2 mg/$2,430
E. coli
GST
40.0 kDa
10 µg/$339; 50 µg/$802; 100 µg/$1,214; 200 µg/$1,430; 1 mg/$2,728; 500 µg/$2,223; 5 mg/$5,601; 2 mg/$2,988
E. coli
His
20.0 kDa
10 µg/$294; 50 µg/$522; 100 µg/$832; 200 µg/$1,034; 1 mg/$2,192; 500 µg/$1,712; 5 mg/$3,641; 2 mg/$2,383
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
27kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
25kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
HEK 293 Cells
Myc-DDK (Flag)
25.7 kDa
20 µg/$1,107
HEK 293 Cells
His, N-Terminal
~13 kDa
200 µl/$283
HEK 293 Cells
His, N-Terminal
~28 kDa
100 µg/$298
HEK 293 Cells
His, N-Terminal
~13 kDa
100 µg/$298
HEK 293 Cells
His, N-Terminal
~28 kDa
200 µl/$283
HEK 293 Cells
Myc-DDK (Flag)
27.82 kDa
100 µg/$494
HEK 293 Cells
Myc-DDK (Flag)
25.7 kDa
100 µg/$494
HEK 293 Cells
Myc-DDK (Flag)
25.7 kDa
100 µg/$494
HEK 293 Cells
Myc-DDK (Flag)
25.7 kDa
100 µg/$494
293T Cells
Myc-DDK (Flag)
27.85 kDa
20 µg/$150
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of 64
product results
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