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BDKRB2/Bradykinin B2 Receptor

bradykinin receptor B2

BDKRB2/Bradykinin B2 Receptor is a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein.

Gene Name:	bradykinin receptor B2
Family/Subfamily:	GPCR , Bradykinin
Synonyms:	BDKRB2, BK-2 receptor, Bradykinin type-2 receptor, B2R, Bradykinin B2 receptor, BRB2, BK-2R, BK-2Rs, BK2, B2 bradykinin receptor, B2bkr, BK-2, BKR2, Bradykinin receptor B2
Target Sequences:	NM_000623 NP_000614.1 P30411

Publications (4)

Expression of endogenous nuclear bradykinin B2 receptors mediating signaling in immediate early gene activation. Savard M, Barbaz D, Blanger S, Mller-Esterl W, Bkaily G, D'orlans-Juste P, Cot J, Bovenzi V, Gobeil F. Journal of cellular physiology. 2008 216:234-44. (Mouse, Human, Rat) [Full Text Article] [PubMed:18264983] Related Antibodies: LS-A797.

Immunohistochemical localization of the bradykinin B1 and B2 receptors in human nasal mucosa. Shirasaki H, Kanaizumi E, Himi T. Mediators of inflammation. 2009 2009:102406. (IHC-P; Human) [Full Text Article] [PubMed:19404481] [PMC:PMC2673475] Related Antibodies: LS-A797.

Targeting intracellular B2 receptors using novel cell-penetrating antagonists to arrest growth and induce apoptosis in human triple-negative breast cancer. Dubuc C, Savard M, Bovenzi V, Lessard A, Fortier A, Côté J, Neugebauer W, Rizzolio F, Geha S, Giordano A, Chemtob S, Gobeil F. Oncotarget. 2018 January;9:9885-9906. (Human) [Full Text Article] [PubMed:29515778] [PMC:PMC5839409] Related Antibodies: LS-A797.

Structure-activity relationships of novel peptide agonists of the human bradykinin B2 receptor. B[Character e9]langer S, Bovenzi V, C[Character f4]t[Character e9] J, Neugebauer W, Amblard M, Martinez J, Lammek B, Savard M, Gobeil F. Peptides. 2009 Apr;30:777-87. [Full Text Article] [PubMed:19111586] Related Antibodies: LS-A797.

Rat BDKRB2/Bradykinin B2 Receptor (Sandwich ELISA) ELISA Kit - LS-F8417

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$783

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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