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BCL2L11 / BIM

BCL2-like 11 (apoptosis facilitator)

BCL2L11 / BIM belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified.

Gene Name: BCL2-like 11 (apoptosis facilitator)
Family/Subfamily: Apoptosis
Synonyms: BCL2L11, BIM-alpha6, BIM-beta7, Bcl-2-like protein 11, BIM-beta6, BimL, BimS, Bcl-2 interacting protein Bim, BimEL, BAM, Bcl2-L-11, BIM, BOD
Target Sequences: NM_006538 O43521 O43521

☰ Filters
Products
Proteins (12)
Over-Expression Lysate (2)
Recombinant (10)
BCL2L11 / BIM (12)
No (12)
6His, N-terminus (2)
GST (2)
GST, N-terminus (1)
His (2)
His,N-terminus (1)
His-SUMO (1)
His-T7 (1)
Myc-DDK (Flag) (2)
Human (10)
Mouse (1)
293T Cells (1)
E. coli (6)
HEK 293 Cells (1)
Wheat Germ Extract (3)
Yeast (1)
Purified (4)
Low endotoxin level (2)
BCL2L11 / BIM Protein
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E. coli
His
50 µg/$361; 250 µg/$739; 10 µg/$261; 20 µg/$298; 100 µg/$454; 500 µg/$1,177
BCL2L11 / BIM Protein
Select
Yeast
His
24.17 kD
100 µg/$446; 20 µg/$336; 1 mg/$1,460
BCL2L11 / BIM Protein - 12.5% SDS-PAGE of human BCL2L11 stained with Coomassie Blue
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Wheat Germ Extract
GST
38.7 kDa
10 µg/$479; 25 µg/$670
BCL2L11 / BIM Protein - 12.5% SDS-PAGE of human BCL2L11 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
38.8 kDa
10 µg/$479; 25 µg/$670
Select
E. coli
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
15kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,353
BCL2L11 / BIM Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
BCL2L11 / BIM Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
15.8 kDa
20 µg/$150
BCL2L11 / BIM Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
15.8 kDa
100 µg/$494
Select
E. coli
His,N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
15 kDa
20 µg/$251; 100 µg/$281
BCL2L11 / BIM Protein
Select
E. coli
His-SUMO
38.17 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
BCL2L11 / BIM Protein
Select
E. coli
6His, N-terminus
10 kDa
50 µg/$315; 100 µg/$365
BCL2L11 / BIM Protein - Recombinant Bcl2 Like Protein 11 By SDS-PAGE
Select
E. coli
His-T7
17.3 kDa
10 µg/$283; 50 µg/$457; 100 µg/$732; 200 µg/$912; 1 mg/$2,032; 500 µg/$1,567; 5 mg/$3,193; 2 mg/$2,219
Viewing 1-12 of 12 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).