BBS2 / BBS

Bardet-Biedl syndrome 2

The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization.

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Antibodies (17)

Proteins (3)

Type

Over-Expression Lysate (2)

Primary (17)

Recombinant (1)

Target

BBS2 / BBS (20)

Reactivity

Human (15)

Mouse (6)

Rat (3)

Bat (6)

Bovine (6)

Chicken (3)

Chimpanzee (3)

Dog (6)

Gibbon (6)

Guinea pig (3)

Horse (6)

Monkey (3)

Orangutan (6)

Rabbit (6)

Zebrafish (6)

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Application

IHC (4)

IHC-P (2)

WB (16)

ELISA (4)

IF (2)

IP (1)

Peptide-ELISA (1)

Host

rabbit (15)

mouse (2)

Isotype

IgG (7)

IgG2a (1)

Clonality

monoclonal mc (1)

polyclonal pc (16)

Format

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

Unconjugated (11)

Epitope

aa151-200 (4)

aa315-364 (4)

Publications

No (20)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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BBS2 / BBS Antibody LS-C675413

Antibody:

BBS2 / BBS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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BBS2 / BBS Antibody LS-C659990

Antibody:

BBS2 / BBS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

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BBS2 / BBS Antibody LS-C659992

Antibody:

BBS2 / BBS Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$351

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BBS2 / BBS Antibody LS-C682088

Antibody:

BBS2 / BBS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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BBS2 / BBS Antibody LS-C802601

Antibody:

BBS2 / BBS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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BBS2 / BBS Antibody LS-C409154

Antibody:

BBS2 / BBS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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BBS2 / BBS Antibody LS-C772600

Antibody:

BBS2 / BBS Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse, Rat

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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BBS2 / BBS Antibody LS-C482827

Antibody:

BBS2 / BBS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321; 200 µl/$386

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BBS2 / BBS Antibody (aa315-364) LS-C135606

Antibody:

BBS2 / BBS Rabbit anti-Human Polyclonal (aa315-364) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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BBS2 / BBS Antibody (aa315-364, HRP) LS-C466686

Antibody:

BBS2 / BBS Rabbit anti-Human Polyclonal (aa315-364) (HRP) Antibody

Reactivity:

Chicken, Zebrafish, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Human, Gibbon, Orangutan

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

BBS2 / BBS Antibody (aa315-364, Biotin) LS-C466684

Antibody:

BBS2 / BBS Rabbit anti-Human Polyclonal (aa315-364) (Biotin) Antibody

Reactivity:

Chicken, Zebrafish, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Human, Gibbon, Orangutan

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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BBS2 / BBS Antibody (aa315-364, FITC) LS-C466685

Antibody:

BBS2 / BBS Rabbit anti-Human Polyclonal (aa315-364) (FITC) Antibody

Reactivity:

Chicken, Zebrafish, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Human, Gibbon, Orangutan

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

BBS2 / BBS Antibody (aa151-200) LS-C135607

Antibody:

BBS2 / BBS Rabbit anti-Human Polyclonal (aa151-200) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

BBS2 / BBS Antibody (aa151-200, HRP) LS-C466689

Antibody:

BBS2 / BBS Rabbit anti-Human Polyclonal (aa151-200) (HRP) Antibody

Reactivity:

Zebrafish, Horse, Rabbit, Dog, Guinea pig, Bovine, Bat, Gibbon, Human, Monkey, Orangutan, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

BBS2 / BBS Antibody (aa151-200, Biotin) LS-C466687

Antibody:

BBS2 / BBS Rabbit anti-Human Polyclonal (aa151-200) (Biotin) Antibody

Reactivity:

Zebrafish, Horse, Rabbit, Dog, Guinea pig, Bovine, Bat, Gibbon, Human, Monkey, Orangutan, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

BBS2 / BBS Antibody (aa151-200, FITC) LS-C466688

Antibody:

BBS2 / BBS Rabbit anti-Human Polyclonal (aa151-200) (FITC) Antibody

Reactivity:

Zebrafish, Horse, Rabbit, Dog, Guinea pig, Bovine, Bat, Gibbon, Human, Monkey, Orangutan, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

BBS2 / BBS Antibody LS-C306507

Antibody:

BBS2 / BBS Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$705

Select

Human BBS2 / BBS Protein (Recombinant GST) (Full Length) - LS-G27602

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

106.3 kDa

Price:

10 µg/$479; 25 µg/$670

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BBS2 / BBS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102008

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

79.7 kDa

Price:

100 µg/$494

Select

Human BBS2 / BBS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G86810

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

79.7 kDa

Price:

20 µg/$150

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