BBS10

Bardet-Biedl syndrome 10

BBS10 is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein's expression impairs ciliogenesis in preadipocytes. Mutations in this gene cause Bardet-Biedl syndrome type 10.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

BBS10 (3)

Publications

No (3)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

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Purified (1)

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Human BBS10 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84303

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

80.7 kDa

Price:

20 µg/$150

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BBS10 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G109835

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

80.7 kDa

Price:

100 µg/$494

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Human BBS10 Protein (Recombinant GST) (Full Length) - LS-G35266

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

43.2 kDa

Price:

10 µg/$479; 25 µg/$670

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