BBS1

Bardet-Biedl syndrome 1

The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization.

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Products

Antibodies (10)

Proteins (4)

Type

Over-Expression Lysate (2)

Primary (10)

Recombinant (2)

Target

BBS1 (14)

Reactivity

Human (8)

Mouse (6)

Rat (3)

Horse (3)

Orangutan (3)

Application

IHC (1)

WB (6)

ELISA (5)

IF (2)

IP (1)

Peptide-ELISA (1)

Host

rabbit (9)

goat (1)

Isotype

IgG (5)

Clonality

polyclonal pc (10)

Format

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

Unconjugated (4)

Epitope

aa110-159 (4)

aa105-463 (1)

aa269-283 (1)

Publications

No (14)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

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BBS1 Antibody LS-C501389

Antibody:

BBS1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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BBS1 Antibody (HRP) LS-C501390

Antibody:

BBS1 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

BBS1 Antibody (Biotin) LS-C501391

Antibody:

BBS1 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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BBS1 Antibody (FITC) LS-C501396

Antibody:

BBS1 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

BBS1 Antibody (aa105-463) LS-C659866

Antibody:

BBS1 Rabbit anti-Human Polyclonal (aa105-463) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

BBS1 Antibody (aa110-159) LS-C135458

Antibody:

BBS1 Rabbit anti-Mouse Polyclonal (aa110-159) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

BBS1 Antibody (aa110-159, HRP) LS-C463857

Antibody:

BBS1 Rabbit anti-Mouse Polyclonal (aa110-159) (HRP) Antibody

Reactivity:

Mouse, Rat, Horse, Orangutan, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

BBS1 Antibody (aa110-159, Biotin) LS-C463855

Antibody:

BBS1 Rabbit anti-Mouse Polyclonal (aa110-159) (Biotin) Antibody

Reactivity:

Mouse, Rat, Horse, Orangutan, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

BBS1 Antibody (aa110-159, FITC) LS-C463856

Antibody:

BBS1 Rabbit anti-Mouse Polyclonal (aa110-159) (FITC) Antibody

Reactivity:

Mouse, Rat, Horse, Orangutan, Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

BBS1 Antibody (aa269-283) LS-C154816

Antibody:

BBS1 Goat anti-Mouse Polyclonal (aa269-283) Antibody

Reactivity:

Mouse

Applications:

Peptide-ELISA

Format:

Unconjugated

Price:

100 µg/$401

Select

Human BBS1 Protein (Recombinant GST, N-terminus) (aa187-295) - LS-G57878

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Select

Human BBS1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83356

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

64.9 kDa

Price:

20 µg/$150

Select

BBS1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G109856

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

64.9 kDa

Price:

100 µg/$494

Select

Human BBS1 Protein (Recombinant GST) (Full Length) - LS-G27600

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

77.8 kDa

Price:

2 µg/$439

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