BAG3 / BAG-3

BCL2-associated athanogene 3

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

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Products

Proteins (5)

Type

Recombinant (5)

Target

BAG3 / BAG-3 (5)

Publications

No (5)

Tag

6His, N-terminus (1)

GST (1)

His (1)

His-SUMO (1)

Myc-DDK (Flag) (1)

Species

Human (3)

Mouse (2)

Source

E. coli (2)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (2)

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Human BAG3 / BAG-3 Protein (Recombinant His) - LS-G665

Source:

E. coli

Tag:

His

Price:

50 µg/$411; 250 µg/$985; 10 µg/$276

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Mouse BAG3 / BAG-3 Protein (Recombinant 6His, N-terminus) (Full Length) - LS-G23459

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

63.7 kD

Price:

100 µg/$499; 20 µg/$364; 1 mg/$1,683

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Mouse BAG3 / BAG-3 Protein (Recombinant His-SUMO) (Full Length) - LS-G21925

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

77.7 kD

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human BAG3 / BAG-3 Protein (Recombinant GST) (Full Length) - LS-G31683

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

88.99 kDa

Price:

10 µg/$479; 25 µg/$670

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Human BAG3 / BAG-3 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70264

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

61.4 kDa

Price:

20 µg/$1,107

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