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BACH2

BTB and CNC homology 1, basic leucine zipper transcription factor 2

Transcriptional regulator that acts as repressor or activator. Binds to Maf recognition elements (MARE). Play important roles in coordinating transcription activation and repression by MAFK By similarity. Induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1.

Gene Name: BTB and CNC homology 1, basic leucine zipper transcription factor 2
Synonyms: BACH2, BTBD25, BTB and CNC homolog 2
Target Sequences: NM_021813 NP_068585.1 Q9BYV9

Publications (1)

1
Increase of T and B cells and altered BACH2 expression patterns in bone marrow trephines of imatinib-treated patients with chronic myelogenous leukaemia. Von Laffert M, Hänel M, Dietel M, Anagnostopoulos I, Jöhrens K. Oncology letters. 2016 October;12:2421-2428. (Human) [Full Text Article] [PubMed:27698808] [PMC:PMC5038374] Related Antibodies: LS-B3533.

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
BACH2 (5)
No (5)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
BACH2 Protein - 12.5% SDS-PAGE of human BACH2 stained with Coomassie Blue
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Wheat Germ Extract
GST
119 kDa
10 µg/$479; 25 µg/$670
BACH2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
92.4 kDa
20 µg/$215
BACH2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
92.4 kDa
100 µg/$710
BACH2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
BACH2 Protein - Purified recombinant protein BACH2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
92.4 kDa
20 µg/$1,107
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).