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B1R / BDKRB1
bradykinin receptor B1
Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | bradykinin receptor B1 |
| Family/Subfamily: | GPCR , Bradykinin |
| Synonyms: | BDKRB1, BKB1R, Bradykinin receptor 1, B1BKR, B1R, Bk b1 receptor, BK-1 receptor, BRADYB1, Bradykinin receptor B1, Kinin b1 receptor, B1 bradykinin receptor, BKR1, Bradykinin B1 receptor |
| Target Sequences: | NM_000710 NP_000701.2 P46663 |
Publications (3)
1
Immunohistochemical localization of the bradykinin B1 and B2 receptors in human nasal mucosa. Shirasaki H, Kanaizumi E, Himi T. Mediators of inflammation. 2009 2009:102406. (IHC-P; Human)
[Full Text Article]
[PubMed:19404481]
[PMC:PMC2673475]
Related Antibodies: LS-A3580.
2
Induction of selective blood-tumor barrier permeability and macromolecular transport by a biostable kinin B1 receptor agonist in a glioma rat model. Ct J, Bovenzi V, Savard M, Dubuc C, Fortier A, Neugebauer W, Tremblay L, Mller-Esterl W, Tsanaclis AM, Lepage M, Fortin D, Gobeil F. PloS one. 2012 7:e37485. (WB; Human)
[Full Text Article]
[PubMed:22629405]
[PMC:PMC3357387]
Related Antibodies: LS-A799.
3
Structure-activity relationships of novel peptide agonists of the human bradykinin B2 receptor. B[Character e9]langer S, Bovenzi V, C[Character f4]t[Character e9] J, Neugebauer W, Amblard M, Martinez J, Lammek B, Savard M, Gobeil F. Peptides. 2009 Apr;30:777-87. [Full Text Article]
[PubMed:19111586]
Related Antibodies: LS-A799.
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(31)
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(2)
Neuroscience
B1R / BDKRB1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
Neuroscience
B1R / BDKRB1 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Human
IHC-P
Unconjugated
50 µg/$440
Neuroscience
Fast Shipping
B1R / BDKRB1 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
B1R / BDKRB1 Mouse anti-Human Monoclonal (3A2) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
B1R / BDKRB1 Goat anti-Human Polyclonal (aa322-333) Antibody
Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
B1R / BDKRB1 Rabbit anti-Human Polyclonal (aa213-239) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
B1R / BDKRB1 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ICC, IF, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
B1R / BDKRB1 Rabbit anti-Human Polyclonal (180-260 aa, Internal) Antibody
Human
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
B1R / BDKRB1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$357
B1R / BDKRB1 Rabbit anti-Human Polyclonal (aa213-239) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
B1R / BDKRB1 Rabbit anti-Human Polyclonal (aa213-239) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
B1R / BDKRB1 Rabbit anti-Human Polyclonal (aa213-239) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
B1R / BDKRB1 Rabbit anti-Human Polyclonal (aa213-239) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
B1R / BDKRB1 Rabbit anti-Human Polyclonal (aa213-239) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
B1R / BDKRB1 Rabbit anti-Human Polyclonal (aa213-239) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
B1R / BDKRB1 Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
B1R / BDKRB1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
B1R / BDKRB1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$937
B1R / BDKRB1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$937
B1R / BDKRB1 Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$937
B1R / BDKRB1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
B1R / BDKRB1 Rabbit anti-Human Polyclonal (aa230-279) Antibody
Human
WB
Unconjugated
100 µl/$424
B1R / BDKRB1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
B1R / BDKRB1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$412
B1R / BDKRB1 Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
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