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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
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Customer Service: (800) 227-6666 / (650) 697-3600
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AZI2 / NAP1
5-azacytidine induced 2
Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1.
| Gene Name: | 5-azacytidine induced 2 |
| Synonyms: | AZI2, 5-azacytidine induced 2, 5-azacytidine induced gene 2, Nak-associated protein 1, NAP1, TILP, AZ2 |
| Target Sequences: | NM_022461 NP_071906.1 Q9H6S1 |
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