AURKC / Aurora C

aurora kinase C

Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Plays also a role in meiosis and more particularly in spermatogenesis. Has redundant cellular functions with AURKB and can rescue an AURKB knockdown. Like AURKB, AURKC phosphorylates histone H3 at 'Ser-10' and 'Ser-28'. Phosphorylates TACC1, another protein involved in cell division, at 'Ser-228'.

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Products

Proteins (7)

Type

Over-Expression Lysate (2)

Recombinant (5)

Target

AURKC / Aurora C (7)

Publications

No (7)

Tag

GST (1)

GST, N-terminus (1)

His-T7 (3)

Myc-DDK (Flag) (2)

Species

Human (4)

Mouse (1)

Rat (1)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

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Mouse AURKC / Aurora C Protein (Recombinant His-T7) (aa5-237) - LS-G24769

Source:

E. coli

Tag:

His-T7

Molecular Weight:

31.0 kDa

Price:

10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164

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Human AURKC / Aurora C Protein (Recombinant GST) (Full Length) - LS-G30579

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

62 kDa

Price:

10 µg/$479; 25 µg/$670

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Human AURKC / Aurora C Protein (Recombinant GST, N-terminus) (aa186-275) - LS-G60245

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human AURKC / Aurora C Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84372

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.4 kDa

Price:

20 µg/$150

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AURKC / Aurora C Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121637

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.4 kDa

Price:

100 µg/$494

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Human AURKC / Aurora C Protein (Recombinant His-T7) (aa20-277) - LS-G24768

Source:

E. coli

Tag:

His-T7

Molecular Weight:

33.7 kDa

Price:

10 µg/$275; 50 µg/$407; 100 µg/$652; 200 µg/$812; 1 mg/$1,893; 500 µg/$1,444; 5 mg/$2,843; 2 mg/$2,077

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Rat AURKC / Aurora C Protein (Recombinant His-T7) (aa92-339) - LS-G24770

Source:

E. coli

Tag:

His-T7

Molecular Weight:

32.7 kDa

Price:

10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164

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