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AURKC / Aurora C
aurora kinase C
Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Plays also a role in meiosis and more particularly in spermatogenesis. Has redundant cellular functions with AURKB and can rescue an AURKB knockdown. Like AURKB, AURKC phosphorylates histone H3 at 'Ser-10' and 'Ser-28'. Phosphorylates TACC1, another protein involved in cell division, at 'Ser-228'.
| Gene Name: | aurora kinase C |
| Family/Subfamily: | Protein Kinase , Aurora/IPL1-like |
| Synonyms: | AURKC, AIE2, Aie1, AIRK3, ARK-3, Aurora kinase C, Aurora-related kinase 3, AurC, Aurora 3, Aurora C, Aurora/IPL1-related kinase 3, ARK3, Aurora-C, AIK3, HsAIRK3, SPGF5, Aurora/IPL1/Eg2 protein 2, STK13 |
| Target Sequences: | NM_003160 NP_003151.2 Q9UQB9 |
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(72)
Type
Primary
(72)
Target
AURKC / Aurora C
(72)
Reactivity
Human
(55)
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(11)
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(11)
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(3)
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(7)
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(69)
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(15)
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(24)
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(64)
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(7)
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(1)
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(32)
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(6)
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monoclonal mc
(6)
polyclonal pc
(66)
Clone
OTI10A7
(2)
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APC
(3)
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(7)
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(3)
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(9)
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(3)
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(3)
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(3)
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(9)
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(9)
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(7)
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(25)
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(14)
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(8)
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(8)
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(1)
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(1)
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Publications
No
(72)
AURKC / Aurora C Mouse anti-Human Monoclonal (OTI10A7) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
AURKC / Aurora C Mouse anti-Human Monoclonal (Carrier-free) (OTI10A7) Antibody
Human
IF, WB
Unconjugated, Carrier-free
100 µg/$511
AURKC / Aurora C Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
200 µl/$460
AURKC / Aurora C Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
AURKC / Aurora C Mouse anti-Human Monoclonal (OTI2B7) Antibody
IHC, IHC-P, WB
Unconjugated
100 µl/$434
AURKC / Aurora C Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
ELISA, IF, WB
Unconjugated
200 µl/$734
AURKC / Aurora C Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Human
ELISA, ICC, IF, WB
Biotin Conjugated
200 µl/$952
AURKC / Aurora C Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Human
ELISA, ICC, IF, WB
FITC Conjugated
200 µl/$952
AURKC / Aurora C Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Human
ELISA, ICC, IF, WB
APC Conjugated
200 µl/$952
AURKC / Aurora C Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody
Human
ELISA, ICC, IF, WB
HRP Conjugated, Azide-free
200 µl/$952
AURKC / Aurora C Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Human
ELISA, ICC, IF, WB
PE Conjugated
200 µl/$952
AURKC / Aurora C Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
ELISA, IF, WB
Unconjugated
200 µl/$734
AURKC / Aurora C Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Human
ELISA, ICC, IF, WB
Biotin Conjugated
200 µl/$952
AURKC / Aurora C Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Human
ELISA, ICC, IF, WB
FITC Conjugated
200 µl/$952
AURKC / Aurora C Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Human
ELISA, ICC, IF, WB
APC Conjugated
200 µl/$952
AURKC / Aurora C Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Human
ELISA, ICC, IF, WB
PE Conjugated
200 µl/$952
AURKC / Aurora C Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody
Human
ELISA, ICC, IF, WB
HRP Conjugated, Azide-free
200 µl/$952
AURKC / Aurora C Rabbit anti-Human Polyclonal (aa115-145) Antibody
Human
ELISA, IF, WB
Unconjugated
200 µl/$734
AURKC / Aurora C Rabbit anti-Human Polyclonal (aa115-145) (Biotin) Antibody
Human
ELISA, ICC, IF, WB
Biotin Conjugated
200 µl/$952
AURKC / Aurora C Rabbit anti-Human Polyclonal (aa115-145) (FITC) Antibody
Human
ELISA, ICC, IF, WB
FITC Conjugated
200 µl/$952
AURKC / Aurora C Rabbit anti-Human Polyclonal (aa115-145) (PE) Antibody
Human
ELISA, ICC, IF, WB
PE Conjugated
200 µl/$952
AURKC / Aurora C Rabbit anti-Human Polyclonal (aa115-145) (Azide-free) (HRP) Antibody
Human
ELISA, ICC, IF, WB
HRP Conjugated, Azide-free
200 µl/$952
AURKC / Aurora C Rabbit anti-Human Polyclonal (aa115-145) (APC) Antibody
Human
ELISA, ICC, IF, WB
APC Conjugated
200 µl/$952
AURKC / Aurora C Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
AURKC / Aurora C Rabbit anti-Human Polyclonal (Lys255) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
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of 72
product results
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