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AUP1

Ancient Ubiquitous Protein 1

The protein encoded this gene is involved in several pathways including quality control of misfolded proteins in the endoplasmic reticulum and lipid droplet accumulation. Lipid droplets are organelles in the cytoplasm that store neutral lipids such as cholesterol esters and trigylycerides to prevent the overabundance of free cholesterol and fatty acids in cells, but also to act as storage for other metabolic processes, such as membrane biogenesis. Reduced expression of this gene results in reduced lipid droplet clustering, a function that is dependent on ubiquitination of the protein. This protein contains multiple domains including a hydrophobic N-terminal domain, an acetyltranferase domain, a ubiquitin-binding CUE domain, and a UBE2B2-binding domain (G2BR). Alternative splicing results in multiple transcript variants.

Gene Name: Ancient Ubiquitous Protein 1
Synonyms: AUP1, Ancient ubiquitous protein 1
Target Sequences: NM_181575 NP_853553.1 Q9Y679

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Proteins (3)
Recombinant (3)
AUP1 (3)
No (3)
GST (1)
His-GST (1)
His-T7 (1)
Human (2)
Mouse (1)
E. coli (2)
Wheat Germ Extract (1)
Purified (1)
AUP1 Protein - Recombinant  Ancient Ubiquitous Protein 1 By SDS-PAGE
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E. coli
His-T7
27.2 kDa
10 µg/$272; 50 µg/$387; 100 µg/$620; 200 µg/$772; 1 mg/$1,834; 500 µg/$1,393; 5 mg/$2,794; 2 mg/$2,016
AUP1 Protein - Recombinant Ancient Ubiquitous Protein 1 By SDS-PAGE
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E. coli
His-GST
53.7 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
AUP1 Protein - 12.5% SDS-PAGE of human AUP1 stained with Coomassie Blue
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Wheat Germ Extract
GST
72.2 kDa
10 µg/$479; 25 µg/$670
Viewing 1-3 of 3 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).