ATXN3 / JOS

ataxin 3

Deubiquitinating enzyme involved in protein homeostasis maintenance, transcription, cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. Binds long polyubiquitin chains and trims them, while it has weak or no activity against chains of 4 or less ubiquitins. Involved in degradation of misfolded chaperone substrates via its interaction with STUB1/CHIP: recruited to monoubiquitinated STUB1/CHIP, and restricts the length of ubiquitin chain attached to STUB1/CHIP substrates and preventing further chain extension. In response to misfolded substrate ubiquitination, mediates deubiquitination of monoubiquitinated STUB1/CHIP. Interacts with key regulators of transcription and represses transcription: acts as a histone-binding protein that regulates transcription.

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Products

Antibodies (35)

Type

Primary (35)

Target

ATXN3 / JOS (35)

Reactivity

Human (35)

Mouse (10)

Rat (9)

Bovine (4)

Cat (1)

Chicken (1)

Chimpanzee (3)

Dog (2)

Donkey (1)

Gibbon (3)

Goat (1)

Guinea pig (1)

Hamster (1)

Horse (4)

Monkey (4)

Pig (4)

Rabbit (1)

Sheep (4)

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Application

IHC (28)

IHC-P (13)

WB (32)

Flo (4)

ELISA (16)

IF (3)

Peptide-ELISA (1)

Host

rabbit (32)

mouse (1)

goat (2)

Product Group

IHCPlus (1)

Isotype

IgG (25)

IgG1,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (34)

Format

APC Conjugated (1)

Azide-free (2)

Biotin Conjugated (3)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (2)

Unconjugated (21)

Epitope

aa29-59 (7)

aa1-288 (4)

aa35-84 (4)

aa267-297 (3)

aa1-245 (1)

aa120-250 (1)

aa226-254 (1)

aa261-288 (1)

Publications

No (35)

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ATXN3 / JOS Antibody (aa1-288) LS-C369297

Antibody:

ATXN3 / JOS Rabbit anti-Human Polyclonal (aa1-288) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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ATXN3 / JOS Antibody (aa1-288, HRP) LS-C369298

Antibody:

ATXN3 / JOS Rabbit anti-Human Polyclonal (aa1-288) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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ATXN3 / JOS Antibody (aa1-288, Biotin) LS-C369301

Antibody:

ATXN3 / JOS Rabbit anti-Human Polyclonal (aa1-288) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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ATXN3 / JOS Antibody (aa1-288, FITC) LS-C369299

Antibody:

ATXN3 / JOS Rabbit anti-Human Polyclonal (aa1-288) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

ATXN3 / JOS Antibody LS-C331383

Antibody:

ATXN3 / JOS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

ATXN3 / JOS Antibody (aa35-84) LS-B11516

Antibody:

ATXN3 / JOS Rabbit anti-Human Polyclonal (aa35-84) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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ATXN3 / JOS Antibody (aa1-245) LS-C186388

Antibody:

ATXN3 / JOS Rabbit anti-Human Polyclonal (aa1-245) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$450

Select

ATXN3 / JOS Antibody (aa261-288) LS-C156684

Antibody:

ATXN3 / JOS Rabbit anti-Human Polyclonal (aa261-288) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

ATXN3 / JOS Antibody (aa267-297, Azide-free, HRP) LS-C252094

Antibody:

ATXN3 / JOS Rabbit anti-Human Polyclonal (aa267-297) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$665

Select

ATXN3 / JOS Antibody (aa267-297, PE) LS-C252095

Antibody:

ATXN3 / JOS Rabbit anti-Human Polyclonal (aa267-297) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$665

Select

ATXN3 / JOS Antibody (aa267-297, FITC) LS-C252093

Antibody:

ATXN3 / JOS Rabbit anti-Human Polyclonal (aa267-297) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$665

Select

ATXN3 / JOS Antibody (aa226-254) LS-C407637

Antibody:

ATXN3 / JOS Rabbit anti-Human Polyclonal (aa226-254) Antibody

Reactivity:

Dog, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

ATXN3 / JOS Antibody (aa29-59) LS-C326893

Antibody:

ATXN3 / JOS Rabbit anti-Human Polyclonal (aa29-59) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

ATXN3 / JOS Antibody (aa29-59, Biotin) LS-C275320

Antibody:

ATXN3 / JOS Rabbit anti-Human Polyclonal (aa29-59) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

ATXN3 / JOS Antibody (aa29-59, FITC) LS-C275321

Antibody:

ATXN3 / JOS Rabbit anti-Human Polyclonal (aa29-59) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

ATXN3 / JOS Antibody (aa29-59, APC) LS-C275319

Antibody:

ATXN3 / JOS Rabbit anti-Human Polyclonal (aa29-59) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

ATXN3 / JOS Antibody (aa29-59, Azide-free, HRP) LS-C275322

Antibody:

ATXN3 / JOS Rabbit anti-Human Polyclonal (aa29-59) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

ATXN3 / JOS Antibody (aa29-59, PE) LS-C275323

Antibody:

ATXN3 / JOS Rabbit anti-Human Polyclonal (aa29-59) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

ATXN3 / JOS Antibody (aa29-59) LS-C99629

Antibody:

ATXN3 / JOS Rabbit anti-Human Polyclonal (aa29-59) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

ATXN3 / JOS Antibody LS-C490103

Antibody:

ATXN3 / JOS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$575

Select

ATXN3 / JOS Antibody LS-C806141

Antibody:

ATXN3 / JOS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

ATXN3 / JOS Antibody LS-C764765

Antibody:

ATXN3 / JOS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

ATXN3 / JOS Antibody LS-C763485

Antibody:

ATXN3 / JOS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$250; 60 µl/$286; 120 µl/$349; 200 µl/$439

Select

ATXN3 / JOS Antibody LS-C831903

Antibody:

ATXN3 / JOS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

ATXN3 / JOS Antibody LS-C192505

Antibody:

ATXN3 / JOS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

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