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ATXN2 / SCA2 / Ataxin-2

ataxin 2

The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. Defects in this gene are the cause of spinocerebellar ataxia type 2 (SCA2). SCA2 belongs to the autosomal dominant cerebellar ataxias type I (ADCA I) which are characterized by cerebellar ataxia in combination with additional clinical features like optic atrophy, ophthalmoplegia, bulbar and extrapyramidal signs, peripheral neuropathy and dementia. SCA2 is caused by expansion of a CAG repeat in the coding region of this gene. This locus has been mapped to chromosome 12, and it has been determined that the diseased allele contains 37-50 CAG repeats, compared to 17-29 in the normal allele. Longer expansions result in earlier onset of the disease. Alternatively spliced transcript variants encoding different isoforms have been identified but their full length sequence has not been determined.

Gene Name: ataxin 2
Synonyms: ATXN2, ASL13, Ataxin 2, ATX2, Ataxin-2, SCA2, TNRC13
Target Sequences: NM_002973 NP_002964.3 Q99700

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ELISA Kits (8)
Sandwich (8)
ATXN2 / SCA2 / Ataxin-2 (8)
Human (1)
Mouse (1)
Rat (1)
Chicken (1)
Guinea pig (1)
Monkey (1)
Porcine (1)
Rabbit (1)
12 x 8-Well Microstrips (1)
96-Well Strip Plate (7)
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Plasma (4)
Serum (4)
ATXN2 / SCA2 / Ataxin-2 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
ATXN2 / SCA2 / Ataxin-2 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$771
ATXN2 / SCA2 / Ataxin-2 ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
ATXN2 / SCA2 / Ataxin-2 ELISA Kit
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Sandwich
12 x 8-Well Microstrips
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
ATXN2 / SCA2 / Ataxin-2 ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
ATXN2 / SCA2 / Ataxin-2 ELISA Kit
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Sandwich
96-Well Strip Plate
Guinea pig
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
ATXN2 / SCA2 / Ataxin-2 ELISA Kit
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Sandwich
96-Well Strip Plate
Porcine
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
ATXN2 / SCA2 / Ataxin-2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).