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ATRIP

ATR interacting protein

ATRIP is an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: ATR interacting protein
Synonyms: ATRIP, AGS1, ATR-interacting protein, ATR interacting protein
Target Sequences: NM_130384 NP_569055.1 Q8WXE1

Publications (1)

1
Reconstitution of a human ATR-mediated checkpoint response to damaged DNA. Choi JH, Lindsey-Boltz LA, Sancar A. Proceedings of the National Academy of Sciences of the United States of America. 2007 104:13301-6. [PubMed:17686975] [PMC:PMC1941640]

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ATRIP ELISA Kit
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Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
ATRIP ELISA Kit
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Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$534
ATRIP ELISA Kit
Select
Cell-Based Phosphorylation
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).