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ATRIP

ATR interacting protein

ATRIP is an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: ATR interacting protein
Synonyms: ATRIP, AGS1, ATR-interacting protein, ATR interacting protein
Target Sequences: NM_130384 NP_569055.1 Q8WXE1

Publications (1)

1
Reconstitution of a human ATR-mediated checkpoint response to damaged DNA. Choi JH, Lindsey-Boltz LA, Sancar A. Proceedings of the National Academy of Sciences of the United States of America. 2007 104:13301-6. [PubMed:17686975] [PMC:PMC1941640]

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Products
Antibodies (46)
Primary (46)
ATRIP (46)
Human (46)
Mouse (17)
Rat (15)
Bovine (1)
Dog (2)
Monkey (2)
Non-Human Primate (1)
Sheep (1)
IHC (21)
IHC-P (7)
WB (36)
Flo (5)
DB (7)
ELISA (17)
ICC (2)
IF (14)
IP (4)
Peptide-ELISA (7)
rabbit (36)
mouse (10)
Product Group
IHCPlus (1)
IgG (28)
IgG1 (2)
IgG2a (4)
IgG2b (4)
monoclonal mc (10)
polyclonal pc (36)
OTI1F10 (2)
OTI1G6 (2)
OTI4A8 (2)
OTI5E7 (2)
OTI9A4 (2)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
Carrier-free (5)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (41)
pSer239 (8)
aa42-309 (7)
pSer224 (4)
pSer68 (4)
10-90 aa (2)
160-240 aa (2)
aa1-260 (2)
aa100-150 (2)
Asp64 (1)
N-Terminus (1)
aa190-239 (1)
aa34-83 (1)
p68/72 (1)
No (46)
ATRIP Antibody - IHC of paraffin-embedded Human breast tissue using anti-ATRIP mouse monoclonal antibody.
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ATRIP Mouse anti-Human Monoclonal (OTI5E7) Antibody
Dog, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
ATRIP Antibody - IHC of paraffin-embedded Human breast tissue using anti-ATRIP mouse monoclonal antibody.
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ATRIP Mouse anti-Human Monoclonal (aa42-309) (Carrier-free) (OTI5E7) Antibody
Dog, Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ATRIP Antibody - Immunohistochemical analysis of ATRIP staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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ATRIP Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
Flo, ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
ATRIP Antibody - Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using ATRIP Antibody. The picture on the right is blocked with the synthesized peptide.
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ATRIP Rabbit anti-Human Polyclonal (aa34-83) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ATRIP Antibody - Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using ATRIP (Phospho-Ser224) Antibody. The picture on the right is blocked with the phospho peptide.
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ATRIP Rabbit anti-Human Polyclonal (pSer224) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ATRIP Antibody - Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE)
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ATRIP Rabbit anti-Human Polyclonal (aa190-239) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$515
ATRIP Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using ATRIP (Ab-68/72) antibody.
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ATRIP Rabbit anti-Human Polyclonal (p68/72) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
ATRIP Antibody - Western blot of ATRIP expression in NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
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ATRIP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
ATRIP Antibody - Dot blot of Phospho-ATRIP-S239 Antibody Phospho-specific antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.
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ATRIP Rabbit anti-Human Polyclonal (pSer239) Antibody
Human
DB
Unconjugated
400 µl/$393
ATRIP Antibody - Immunofluorescence analysis of A549 cells.
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ATRIP Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, IP, WB
Unconjugated
20 µl/$275; 100 µl/$389
ATRIP Antibody - Immunohistochemistry of paraffin-embedded human ovary using antibody at 1:100 dilution.
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ATRIP Rabbit anti-Human Polyclonal (aa1-260) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
ATRIP Antibody - Western blot of ATRIP antibody
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ATRIP Rabbit anti-Human Polyclonal (10-90 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ATRIP Antibody - IHC of ATRIP (D64) pAb in paraffin-embedded human lung colon carcinoma tissue.
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ATRIP Rabbit anti-Human Polyclonal (Asp64) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
ATRIP Antibody - Anti-ATRIP mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ATRIP.
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ATRIP Mouse anti-Human Monoclonal (aa42-309) (OTI9A4) Antibody
Human, Monkey
Flo, IF, WB
Unconjugated
100 µl/$434
ATRIP Antibody - Anti-ATRIP mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ATRIP.
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ATRIP Mouse anti-Human Monoclonal (aa42-309) (Carrier-free) (OTI9A4) Antibody
Human, Monkey
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
ATRIP Antibody - Staining NIH-3T3 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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ATRIP Rabbit anti-Human Polyclonal (pSer68) Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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ATRIP Rabbit anti-Human Polyclonal (160-240 aa) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ATRIP Antibody - P-peptide - + Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using ATRIP (Phospho-Ser224) antibody.
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ATRIP Rabbit anti-Human Polyclonal (pSer224) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
ATRIP Antibody - Detection of Human ATRIP by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-ATRIP used at a dilution of 1:1000 (1 ug/ml).
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ATRIP Rabbit anti-Human Polyclonal (aa100-150) Antibody
Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
ATRIP Antibody - Anti-ATRIP mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ATRIP.
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ATRIP Mouse anti-Human Monoclonal (aa42-309) (OTI4A8) Antibody
Human
IF, WB
Unconjugated
100 µl/$434
ATRIP Antibody - Anti-ATRIP mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ATRIP.
Select
ATRIP Mouse anti-Human Monoclonal (aa42-309) (Carrier-free) (OTI4A8) Antibody
Human
IF, WB
Unconjugated, Carrier-free
100 µg/$511
ATRIP Antibody - 1:100 staining mouse lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
ATRIP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ATRIP Antibody - 1:100 staining mouse lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
ATRIP Rabbit anti-Human Polyclonal (pSer224) Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
ATRIP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
Select
ATRIP Rabbit anti-Human Polyclonal (pSer224) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).