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ATP6V1D / V-ATPase subunit D

ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D

ATP6V1D / V-ATPase subunit D is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the V1 domain D subunit protein.

Gene Name: ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
Family/Subfamily: Transporter , ATPase - V type
Synonyms: ATP6V1D, ATP6M, V-ATPase subunit D, VPATPD, V-type proton ATPase subunit D, Vacuolar H-ATPase subunit D, Vacuolar proton pump D subunit, Vacuolar proton pump subunit D, VMA8, V-ATPase d subunit, Vacuolar ATPase subunit D, VATD
Target Sequences: NM_015994 NP_057078.1 Q9Y5K8

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Proteins (2)
Recombinant (2)
ATP6V1D / V-ATPase subunit D (2)
No (2)
GST (1)
GST, N-terminus (1)
Human (2)
Wheat Germ Extract (2)
Purified (1)
ATP6V1D / V-ATPase subunit D Protein - 12.5% SDS-PAGE of human ATP6V1D stained with Coomassie Blue
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Wheat Germ Extract
GST
52.91 kDa
2 µg/$439
ATP6V1D / V-ATPase subunit D Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).