ATP6V1B1

ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1

ATP6V1B1 is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness.

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Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

ATP6V1B1 (5)

Publications

No (5)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human ATP6V1B1 Protein (Recombinant GST, N-terminus) (aa1-75) - LS-G57857

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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ATP6V1B1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99519

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.7 kDa

Price:

100 µg/$494

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Human ATP6V1B1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67312

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.7 kDa

Price:

20 µg/$1,107

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Human ATP6V1B1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79522

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.7 kDa

Price:

20 µg/$150

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Human ATP6V1B1 Protein (Recombinant GST) (Full Length) - LS-G27581

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

81.95 kDa

Price:

10 µg/$479; 25 µg/$670

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