Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha3beta3 subcomplex and subunit a/ATP6 static relative to the rotary elements.
Gene Name: | ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit |
Family/Subfamily: | Transporter , ATPase - F type |
Synonyms: | ATP5O, ATPO, OSCP |
Target Sequences: | NM_001697 NP_001688.1 P48047 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.