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ATP2B1 / PMCA1

ATPase, Ca++ transporting, plasma membrane 1

ATP2B1 / PMCA1 belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Name: ATPase, Ca++ transporting, plasma membrane 1
Family/Subfamily: Transporter , ATPase - P type, type IIB
Synonyms: ATP2B1, PMCA1, PMCA1kb, Plasma membrane calcium pump
Target Sequences: NM_001682 NP_001673.2 P20020

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ATP2B1 / PMCA1 (5)
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ATP2B1 / PMCA1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
ATP2B1 / PMCA1 ELISA Kit
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Custom
96-Well Strip Plate
Chicken
1 Plate/$783
ATP2B1 / PMCA1 ELISA Kit
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Custom
96-Well Strip Plate
Human
1 Plate/$669
ATP2B1 / PMCA1 ELISA Kit
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Custom
96-Well Strip Plate
Pig
1 Plate/$669
ATP2B1 / PMCA1 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).