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ATP2A1 / SERCA1

ATPase, Ca++ transporting, cardiac muscle, fast twitch 1

ATP2A1 / SERCA1 is one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms.

Gene Name: ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
Family/Subfamily: Transporter , ATPase - P type, type IIA
Synonyms: ATP2A1, SERCA1, ATP2A, Calcium pump 1, SR Ca(2+)-ATPase 1
Target Sequences: NM_004320 NP_004311.1 O14983

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Products
Antibodies (26)
Primary (26)
ATP2A1 / SERCA1 (26)
Human (25)
Mouse (14)
Rat (13)
Bat (4)
Bovine (5)
Chicken (1)
Chimpanzee (4)
Dog (1)
Gibbon (4)
Guinea pig (4)
Horse (4)
Monkey (5)
Pig (4)
Rabbit (6)
Sheep (1)
Zebrafish (3)
IHC (10)
IHC-P (6)
WB (20)
Flo (1)
ELISA (8)
IF (3)
IP (2)
Peptide-ELISA (2)
rabbit (21)
mouse (5)
Product Group
IHCPlus (3)
IgG (16)
IgG1 (3)
IgG1,k (1)
IgG3,k (1)
monoclonal mc (5)
polyclonal pc (21)
1B11 (1)
3D1H6 (1)
4B8 (1)
4F11F6 (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (20)
N-Terminus (4)
520-600 aa, Internal (1)
Asp580 (1)
Internal (1)
aa1-32 (1)
aa548-597 (1)
aa665-680 (1)
No (26)
ATP2A1 / SERCA1 Antibody - Anti-SERCA1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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ATP2A1 / SERCA1 Mouse anti-Human Monoclonal (1B11) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
ATP2A1 / SERCA1 Antibody - Immunohistochemical analysis of SERCA1 staining in human muscle formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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ATP2A1 / SERCA1 Rabbit anti-Human Polyclonal (Internal) Antibody
Rabbit, Mouse, Bovine, Rat, Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$299
ATP2A1 / SERCA1 Antibody - Anti-ATP2A1 / SERCA1 antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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ATP2A1 / SERCA1 Rabbit anti-Human Polyclonal (aa548-597) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
ATP2A1 / SERCA1 Antibody - Anti-SERCA1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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ATP2A1 / SERCA1 Mouse anti-Human Monoclonal (4B8) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µg/$460
ATP2A1 / SERCA1 Antibody - Western blot analysis using ATP2A1 mAb against human ATP2A1 (AA: 487-631) recombinant protein. (Expected MW is 42 kDa)
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ATP2A1 / SERCA1 Mouse anti-Human Monoclonal (3D1H6) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
ATP2A1 / SERCA1 Antibody - Staining HT29 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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ATP2A1 / SERCA1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ATP2A1 / SERCA1 Antibody - ATP2A1 / SERCA1 antibody. IHC(P): Human Placenta Tissue.
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ATP2A1 / SERCA1 Rabbit anti-Human Polyclonal (aa665-680) Antibody
Chicken, Sheep, Bovine, Rat, Pig, Horse, Bat, Rabbit, Mouse, Guinea pig, Human, Monkey
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
ATP2A1 / SERCA1 Antibody - ATP2A1 antibody IHC-paraffin. IHC(P): Rat Skeletal Muscle Tissue.
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ATP2A1 / SERCA1 Rabbit anti-Human Polyclonal (aa1-32) Antibody
Mouse, Rat, Chimpanzee, Gibbon, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
ATP2A1 / SERCA1 Antibody - Western blot of SERCA1 antibody
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ATP2A1 / SERCA1 Rabbit anti-Human Polyclonal (520-600 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ATP2A1 / SERCA1 Antibody - Western blot analysis using ATP2A1 mAb against human ATP2A1 (AA: 487-631) recombinant protein. (Expected MW is 42 kDa)
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ATP2A1 / SERCA1 Mouse anti-Human Monoclonal (4F11F6) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$459
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ATP2A1 / SERCA1 Rabbit anti-Human Polyclonal (Asp580) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$321; 100 µl/$403
ATP2A1 / SERCA1 Antibody - IHC image of ATP2A1 Antibody diluted at 1:300 and staining in paraffin-embedded human skeletal muscle tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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ATP2A1 / SERCA1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF
Unconjugated
50 µg/$294; 100 µg/$360
Select
ATP2A1 / SERCA1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
HRP Conjugated
50 µg/$294; 100 µg/$360
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ATP2A1 / SERCA1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
Biotin Conjugated
50 µg/$294; 100 µg/$360
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ATP2A1 / SERCA1 Mouse anti-Rabbit Monoclonal Antibody
Rabbit, Mouse, Dog, Human
IHC, WB
Unconjugated
100 µl/$1,182
ATP2A1 / SERCA1 Antibody - Immunohistochemistry of paraffin-embedded Human brain using ATP2A1 Polyclonal Antibody at dilution of 1:30.
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ATP2A1 / SERCA1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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ATP2A1 / SERCA1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
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ATP2A1 / SERCA1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP
Unconjugated
100 µg/$341
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ATP2A1 / SERCA1 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat
WB
Unconjugated
100 µl/$688
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ATP2A1 / SERCA1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$688
ATP2A1 / SERCA1 Antibody - ATP2A1 / SERCA1 antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ATP2A1 / SERCA1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human, Monkey
WB
Unconjugated
100 µl/$424
ATP2A1 / SERCA1 Antibody - ATP2A1 / SERCA1 antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ATP2A1 / SERCA1 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Zebrafish, Rat, Rabbit, Mouse, Guinea pig, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$469
ATP2A1 / SERCA1 Antibody - ATP2A1 / SERCA1 antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ATP2A1 / SERCA1 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Zebrafish, Rat, Rabbit, Mouse, Guinea pig, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
ATP2A1 / SERCA1 Antibody - ATP2A1 / SERCA1 antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ATP2A1 / SERCA1 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Zebrafish, Rat, Rabbit, Mouse, Guinea pig, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
ATP2A1 / SERCA1 Antibody - Western blot analysis of extracts of HL-60 cells, using ATP2A1 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
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ATP2A1 / SERCA1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
Viewing 1-25 of 26 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).