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ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP1B1 belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known.
| Gene Name: | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| Family/Subfamily: | Transporter , ATPase - P type, beta subunit |
| Synonyms: | ATP1B1, Adenosinetriphosphatase, ATP1B, Atpb1 |
| Target Sequences: | NM_001677 NP_001668.1 P05026 |
Publications (8)
1
The H,K-ATPase beta subunit as a model to study the role of N-glycosylation in membrane trafficking and apical sorting. Vagin O, Turdikulova S, Sachs G. The Journal of biological chemistry. 2004 279:39026-34.
[PubMed:15247221]
2
Use of the H,K-ATPase beta subunit to identify multiple sorting pathways for plasma membrane delivery in polarized cells. Vagin O, Turdikulova S, Yakubov I, Sachs G. The Journal of biological chemistry. 2005 280:14741-54. (WB; Dog)
[PubMed:15695513]
3
Recombinant addition of N-glycosylation sites to the basolateral Na,K-ATPase beta1 subunit results in its clustering in caveolae and apical sorting in HGT-1 cells. Vagin O, Turdikulova S, Sachs G. The Journal of biological chemistry. 2005 280:43159-67.
[PubMed:16230337]
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ATP1B1 Goat anti-Human Polyclonal (aa85-99) Antibody
Mouse, Dog, Rat, Hamster, Horse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
ATP1B1 Mouse anti-Rabbit Monoclonal (464.8 (8A Beta)) Antibody
Rabbit, Dog, Bovine, Rat, Hamster, Pig, Human
IHC, IHC-P, WB
Unconjugated
0.1 ml/$460
ATP1B1 Rabbit anti-Human Polyclonal (aa201-250) Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
ATP1B1 Rabbit anti-Human Polyclonal (aa201-250) (HRP) Antibody
Mouse, Guinea pig, Rat, Bat, Human
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
ATP1B1 Rabbit anti-Human Polyclonal (aa201-250) (Biotin) Antibody
Mouse, Guinea pig, Rat, Bat, Human
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
ATP1B1 Rabbit anti-Human Polyclonal (aa201-250) (FITC) Antibody
Mouse, Guinea pig, Rat, Bat, Human
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
ATP1B1 Rabbit anti-Human Polyclonal (aa63-112) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
ATP1B1 Rabbit anti-Human Polyclonal (aa63-112) (HRP) Antibody
Mouse, Dog, Guinea pig, Rat, Chimpanzee, Orangutan, Gibbon, Human
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
ATP1B1 Rabbit anti-Human Polyclonal (aa63-112) (Biotin) Antibody
Mouse, Dog, Guinea pig, Rat, Chimpanzee, Orangutan, Gibbon, Human
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
ATP1B1 Rabbit anti-Human Polyclonal (aa63-112) (FITC) Antibody
Mouse, Dog, Guinea pig, Rat, Chimpanzee, Orangutan, Gibbon, Human
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
ATP1B1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
ATP1B1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
ATP1B1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$748
ATP1B1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
ATP1B1 Rabbit anti-Human Polyclonal (aa112-138) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
ATP1B1 Rabbit anti-Human Polyclonal (aa112-138) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
ATP1B1 Rabbit anti-Human Polyclonal (aa112-138) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
ATP1B1 Rabbit anti-Human Polyclonal (aa112-138) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
ATP1B1 Rabbit anti-Human Polyclonal (aa112-138) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
ATP1B1 Rabbit anti-Human Polyclonal (aa112-138) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
ATP1B1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
ATP1B1 Rabbit anti-Human Polyclonal (aa112-138) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
ATP1B1 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321
ATP1B1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
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