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ATP11C
ATPase, class VI, type 11C
Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. Required for B cell differentiation past the pro-B cell stage. Seems to mediate phosphatidylserine (PS) flipping in pro-B cells. May be involved in the transport of cholestatic bile acids.
| Gene Name: | ATPase, class VI, type 11C |
| Family/Subfamily: | Transporter , ATPase - P type, type IV |
| Synonyms: | ATP11C, ATPase IQ, ATPase, class VI, type 11C, ATPIG, ATPase class VI type 11C, ATPIQ |
| Target Sequences: | AJ580093 CAE30472.1 Q8NB49 |
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