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Newark, CA 94560
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ATP11A
ATPase, class VI, type 11A
Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable). May be involved in the uptake of farnesyltransferase inhibitor drugs, such as lonafarnib.
| Gene Name: | ATPase, class VI, type 11A |
| Family/Subfamily: | Transporter , ATPase - P type, type IV |
| Synonyms: | ATP11A, ATPase class VI type 11A, ATPase, class VI, type 11A, KIAA1021, ATPase IS, ATPIH, ATPIS |
| Target Sequences: | AB028944 BAA82973.2 P98196 |
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