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ATOH1 / MATH-1

atonal homolog 1 (Drosophila)

Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription.

Gene Name: atonal homolog 1 (Drosophila)
Synonyms: ATOH1, ATH1, BHLHa14, HATH1, Protein atonal homolog 1, MATH-1, Math1, Atonal homolog 1 (Drosophila)
Target Sequences: NM_005172 NP_005163.1 Q92858

Publications (1)

1
MCPyV Large T Antigen-Induced Atonal Homolog 1 Is a Lineage-Dependency Oncogene in Merkel Cell Carcinoma. Kaiji Fan, Jan Gravemeyer, Cathrin Ritter, Kashif Rasheed, Thilo Gambichler, Ugo Moens, Masahiro Shuda, David Schrama, Jürgen C Becker. The Journal of investigative dermatology. 2020 January;140:56-65.e3. [Full Text Article] [PubMed:31283928] Related Antibodies: LS-B6529.

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Products
Proteins (8)
Over-Expression Lysate (2)
Recombinant (6)
ATOH1 / MATH-1 (8)
No (8)
6His, N-terminus (1)
GST (1)
GST, N-terminus (1)
His, N-Terminal (1)
His-SUMO (1)
Myc-DDK (Flag) (2)
Human (6)
Mouse (1)
293T Cells (1)
E. coli (4)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (3)
ATOH1 / MATH-1 Protein
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E. coli
None
100 µg/$361; 500 µg/$739; 20 µg/$261
ATOH1 / MATH-1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
38 kDa
20 µg/$150
ATOH1 / MATH-1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
ATOH1 / MATH-1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
38 kDa
100 µg/$494
ATOH1 / MATH-1 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His, N-terminus
41.9 kDa
1 mg/$1,679; 100 µg/$500; 20 µg/$364
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E. coli
His, N-Terminal
38 kDa
50 µg/$419
ATOH1 / MATH-1 Protein
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E. coli
His-SUMO
54.1 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
ATOH1 / MATH-1 Protein - 12.5% SDS-PAGE of human ATOH1 stained with Coomassie Blue
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Wheat Germ Extract
GST
64.6 kDa
2 µg/$439
Viewing 1-8 of 8 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).