ATG4A

autophagy related 4A, cysteine peptidase

Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Has also an activity of delipidating enzyme for the PE-conjugated forms.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

ATG4A (5)

Publications

No (5)

Tag

6His, N-terminus (2)

GST (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (2)

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Human ATG4A Protein (Recombinant 6His, N-terminus) (Met1-Val398) - LS-G39664

Source:

E. coli

Tag:

6His, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

47.5kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353

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Human ATG4A Protein (Recombinant GST) (Full Length) - LS-G36212

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

71.8 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ATG4A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82369

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.4 kDa

Price:

20 µg/$150

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ATG4A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G104733

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.4 kDa

Price:

100 µg/$494

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Human ATG4A Protein (Recombinant 6His, N-terminus) (Met1-Val398) - LS-G140057

Source:

E. coli

Tag:

6His, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

47.5 kDa

Price:

10 µg/$344; 50 µg/$584

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