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E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3 (By similarity). Plays a role in adenovirus-mediated cell lysis.
Gene Name: | autophagy related 10 |
Synonyms: | ATG10, Autophagy-related protein 10, Autophagy related 10, APG10-like, DKFZP586I0418, Pp12616, APG10, APG10L |
Target Sequences: | NM_031482 NP_113670.1 Q9H0Y0 |
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