ATF1

activating transcription factor 1

ATF1 is an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6.

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Products

ELISA Kits (10)

Type

Cell-Based (1)

Cell-Based Phosphorylation (1)

Custom (3)

Development Kit (1)

DNA Binding (1)

Sandwich (3)

Target

ATF1 (10)

Reactivity

Human (8)

Mouse (4)

Rat (2)

Product Group

DevKit DuoPlus (1)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (3)

96-Well Strip Plate (5)

Antibody Pair and Standard (1)

Publications

No (10)

Sample Type

Adherent Cell Cultures (2)

Cell Culture Supernatants (2)

Cell Lysates (3)

Nuclear Lysates (1)

Plasma (2)

Serum (2)

Tissue Homogenates (3)

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Mouse/Human/Rat ATF1 (DNA-Binding ELISA) ELISA Kit - LS-F738

Type:

DNA Binding

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Nuclear Lysates

Price:

1 Plate/$694

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Mouse/Human/Rat ATF1 (Cell-Based ELISA) ELISA Kit - LS-F1807

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$534

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Human ATF1 (Custom ELISA) ELISA Kit - LS-F16950

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Mouse ATF1 (Custom ELISA) ELISA Kit - LS-F16951

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Bovine ATF1 (Custom ELISA) ELISA Kit - LS-F16952

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Human ATF1 (Sandwich ELISA) ELISA Kit - LS-F36733

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human ATF1 (Sandwich ELISA) ELISA Kit - LS-F38985

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$798

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DevKit DuoPlus Human ATF1 ELISA Development Kit - LS-F71775

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

500 Wells/$1,229; 1000 Wells/$1,826

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Human ATF1 (Sandwich ELISA) ELISA Kit - LS-F20686

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Mouse/Human Phospho-ATF1 (Ser63) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1119

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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