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ATPase that plays a critical role in regulating the surface expression of AMPA receptors (AMPAR), thereby regulating synaptic plasticity and learning and memory. Required for NMDA-stimulated AMPAR internalization and inhibition of GRIA1 and GRIA2 recycling back to the plasma membrane; these activities are ATPase-dependent.
Gene Name: | ATPase family, AAA domain containing 1 |
Synonyms: | ATAD1, AFDC1, FNP001, THORASE |
Target Sequences: | NM_032810 NP_116199.2 Q8NBU5 |
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