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Aspartate Aminotransferase

glutamic-oxaloacetic transaminase 1, soluble

Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H2S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.

Gene Name: glutamic-oxaloacetic transaminase 1, soluble
Synonyms: GOT1, Aspartate Aminotransferase, ASTQTL1, Growth-inhibiting protein 18, Transaminase A, GIG18
Target Sequences: NM_002079 NP_002070.1 P17174

Publications (2)

1
CXCL14 and MCP1 are potent trophic factors associated with cell migration and angiogenesis leading to higher regenerative potential of dental pulp side population cells. Hayashi Y, Murakami M, Kawamura R, Ishizaka R, Fukuta O, Nakashima M. Stem cell research & therapy. 2015 6:111. (WB; Pig) [Full Text Article] [PubMed:26021377] [PMC:PMC4488059] Related Antibodies: LS-B24.
2
Stimulation of angiogenesis, neurogenesis and regeneration by side population cells from dental pulp. Ishizaka R, Hayashi Y, Iohara K, Sugiyama M, Murakami M, Yamamoto T, Fukuta O, Nakashima M. Biomaterials. 2013 Mar;34:1888-97. [Full Text Article] [PubMed:23245334] Related Antibodies: LS-B24.

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Products
ELISA Kits (25)
Competitive EIA (3)
Custom (3)
Development Kit (3)
Sandwich (16)
Aspartate Aminotransferase (25)
Human (5)
Mouse (7)
Rat (6)
Bovine (2)
Chicken (1)
Pig (2)
Rabbit (1)
Product Group
DevKit DuoPlus (3)
96-Well Microplate (5)
96-Well Strip Plate (17)
Antibody Pair and Standard (3)
No (25)
Cell Culture Supernatants (4)
Cell Lysates (6)
Plasma (22)
Serum (22)
Tissue Homogenates (13)
Aspartate Aminotransferase ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
1.56 - 100 U/l
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Aspartate Aminotransferase ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$798
Aspartate Aminotransferase ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$715
Aspartate Aminotransferase ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
3.12 - 200 U/l
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Aspartate Aminotransferase ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Aspartate Aminotransferase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Bovine
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$816
Aspartate Aminotransferase ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
Aspartate Aminotransferase ELISA Kit
Select
Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$783
Aspartate Aminotransferase ELISA Kit
Select
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$669
Aspartate Aminotransferase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Bovine
0.469 - 30 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Aspartate Aminotransferase ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
3.12 - 200 mIU/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Aspartate Aminotransferase ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
1.56 - 100 mIU/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Aspartate Aminotransferase ELISA Kit
Select
Sandwich
96-Well Microplate
Pig
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$816
Aspartate Aminotransferase ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Rat
1.562 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
500 Wells/$1,305; 1000 Wells/$1,952
Aspartate Aminotransferase ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$834
Aspartate Aminotransferase ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
500 Wells/$1,229; 1000 Wells/$1,826
Aspartate Aminotransferase ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Mouse
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
500 Wells/$1,254; 1000 Wells/$1,867
Aspartate Aminotransferase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$750
Aspartate Aminotransferase ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
Aspartate Aminotransferase ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
Aspartate Aminotransferase ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
Aspartate Aminotransferase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$750
Aspartate Aminotransferase ELISA Kit
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Competitive EIA
96-Well Strip Plate
Rat
10 - 250 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
Aspartate Aminotransferase ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
1 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
Aspartate Aminotransferase ELISA Kit
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Competitive EIA
96-Well Strip Plate
Human
1 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).