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ASL / Argininosuccinate Lyase

argininosuccinate lyase

ASL / Argininosuccinate Lyase encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene Name: argininosuccinate lyase
Synonyms: ASL, ASAL, Argininosuccinate lyase, Argininosuccinase, Arginosuccinase
Target Sequences: NM_000048 NP_000039.2 P04424

☰ Filters
Antibodies (40)
Proteins (12)
ELISA Kits (4)
Custom (2)
Over-Expression Lysate (8)
Primary (40)
Recombinant (4)
Sandwich (2)
ASL / Argininosuccinate Lyase (56)
Human (40)
Mouse (24)
Rat (12)
Bat (9)
Bovine (10)
Chicken (9)
Chimpanzee (6)
Gibbon (3)
Goat (3)
Guinea pig (9)
Hamster (9)
Horse (9)
Monkey (9)
Pig (9)
Rabbit (9)
Xenopus (6)
Zebrafish (9)
IHC (7)
IHC-P (6)
WB (31)
ELISA (6)
ICC (3)
IF (3)
IP (1)
rabbit (34)
mouse (6)
Product Group
IHCPlus (1)
IgG (29)
IgG1 (3)
IgG2a (2)
monoclonal mc (5)
polyclonal pc (35)
OTI14C7 (2)
OTI3D4 (2)
OTI9G2 (1)
96-Well Strip Plate (4)
APC Conjugated (1)
Biotin Conjugated (5)
Carrier-free (3)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (1)
Preservative Free (2)
Unconjugated (23)
aa101-150 (4)
aa260-309 (4)
aa284-333 (4)
aa13-261 (1)
aa86-325 (1)
No (56)
Plasma (2)
Serum (2)
GST (1)
His (1)
Myc-DDK (Flag) (10)
Human (8)
293T Cells (4)
E. coli (1)
HEK 293 Cells (6)
Wheat Germ Extract (1)
Purified (1)
ASL / Argininosuccinate Lyase Protein - Purified recombinant protein ASL was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
51.5 kDa
20 µg/$1,107
ASL / Argininosuccinate Lyase Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
ASL / Argininosuccinate Lyase ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
ASL / Argininosuccinate Lyase Antibody - IHC of paraffin-embedded U87 xenograft using ASL antibody at 1:500 dilution.
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ASL / Argininosuccinate Lyase Rabbit anti-Human Polyclonal (aa13-261) Antibody
Mouse, Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$450
ASL / Argininosuccinate Lyase Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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ASL / Argininosuccinate Lyase Rabbit anti-Human Polyclonal (aa86-325) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
50 µl/$460
ASL / Argininosuccinate Lyase Antibody - Immunofluorescence analysis of HeLa cells.
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ASL / Argininosuccinate Lyase Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
ASL / Argininosuccinate Lyase Antibody - Immunohistochemistry - Anti-Adenylosuccinate Lyase Picoband Antibody
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ASL / Argininosuccinate Lyase Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
ASL / Argininosuccinate Lyase Antibody - Immunohistochemical staining of paraffin-embedded Human endometrium tissue within the normal limits using anti-ASL mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)
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ASL / Argininosuccinate Lyase Mouse anti-Human Monoclonal (Carrier-free) (OTI9G2) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ASL / Argininosuccinate Lyase Antibody - Immunofluorescent analysis of ASL staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
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ASL / Argininosuccinate Lyase Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ICC, IF, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
ASL / Argininosuccinate Lyase Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using ASL Polyclonal Antibody at dilution of 1:35.
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ASL / Argininosuccinate Lyase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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ASL / Argininosuccinate Lyase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
ASL / Argininosuccinate Lyase Antibody - IHC testing of FFPE human breast cancer tissue with ASL antibody at 1ug/ml. Required HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to testing.
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ASL / Argininosuccinate Lyase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
100 µg/$575
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ASL / Argininosuccinate Lyase Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
ASL / Argininosuccinate Lyase Antibody - Arginosuccinate Lyase / ASL antibody Western Blot of Mouse Liver.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ASL / Argininosuccinate Lyase Rabbit anti-Mouse Polyclonal (aa284-333) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$424
ASL / Argininosuccinate Lyase Antibody - Arginosuccinate Lyase / ASL antibody Western Blot of Mouse Liver.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ASL / Argininosuccinate Lyase Rabbit anti-Mouse Polyclonal (aa284-333) (HRP) Antibody
Xenopus, Chicken, Zebrafish, Rat, Hamster, Bat, Pig, Horse, Bovine, Rabbit, Mouse, Goat, Guinea pig, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$469
ASL / Argininosuccinate Lyase Antibody - Arginosuccinate Lyase / ASL antibody Western Blot of Mouse Liver.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ASL / Argininosuccinate Lyase Rabbit anti-Mouse Polyclonal (aa284-333) (FITC) Antibody
Xenopus, Chicken, Zebrafish, Rat, Hamster, Bat, Pig, Horse, Bovine, Rabbit, Mouse, Goat, Guinea pig, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
ASL / Argininosuccinate Lyase Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ASL (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ASL.
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ASL / Argininosuccinate Lyase Mouse anti-Human Monoclonal (OTI14C7) Antibody
Human
WB
Unconjugated
100 µl/$434
ASL / Argininosuccinate Lyase Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY ASL. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ASL.
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ASL / Argininosuccinate Lyase Mouse anti-Human Monoclonal (Carrier-free) (OTI14C7) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
ASL / Argininosuccinate Lyase Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ASL (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ASL.
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ASL / Argininosuccinate Lyase Mouse anti-Human Monoclonal (OTI3D4) Antibody
Human
WB
Unconjugated
100 µl/$434
ASL / Argininosuccinate Lyase Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ASL (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ASL.
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ASL / Argininosuccinate Lyase Mouse anti-Human Monoclonal (Carrier-free) (OTI3D4) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
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ASL / Argininosuccinate Lyase Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
100 µg/$749
ASL / Argininosuccinate Lyase Antibody - Immunochemical staining of mouse ASL in mouse liver with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.
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ASL / Argininosuccinate Lyase Rabbit anti-Mouse Polyclonal (Preservative Free) Antibody
Mouse
IHC-P
Unconjugated, Preservative Free
100 µl/$412
ASL / Argininosuccinate Lyase Antibody - Transfected 293T cell lysate. Antibody concentration: 0.25 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ASL / Argininosuccinate Lyase Rabbit anti-Human Polyclonal (aa101-150) Antibody
Human
WB
Unconjugated
100 µl/$424
ASL / Argininosuccinate Lyase Antibody - Fetal liver cell lysate. Antibody concentration: 5.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ASL / Argininosuccinate Lyase Rabbit anti-Human Polyclonal (aa260-309) Antibody
Human
WB
Unconjugated
100 µl/$397
ASL / Argininosuccinate Lyase Antibody - Immunohistochemistry of paraffin-embedded human liver cancer using ASL Antibody at dilution of 1:100
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ASL / Argininosuccinate Lyase Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
Viewing 1-25 of 56 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).