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ASCC1

activating signal cointegrator 1 complex subunit 1

ASCC1 is a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.

Gene Name: activating signal cointegrator 1 complex subunit 1
Synonyms: ASCC1, ASC1p50, ASC-1 complex subunit p50, p50, CGI-18, Em:AC022392.3, Trip4 complex subunit p50
Target Sequences: NM_015947 NP_057031.2 Q8N9N2

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Proteins (7)
Over-Expression Lysate (4)
Recombinant (3)
ASCC1 (7)
No (7)
GST (1)
His (1)
Myc-DDK (Flag) (5)
Human (5)
293T Cells (2)
E. coli (1)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purified (2)
ASCC1 Protein - 12.5% SDS-PAGE of human ASCC1 stained with Coomassie Blue
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Wheat Germ Extract
GST
67.6 kDa
10 µg/$479; 25 µg/$670
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293T Cells
Myc-DDK (Flag)
41 kDa
20 µg/$150
ASCC1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
46 kDa
20 µg/$150
ASCC1 Protein - Purified recombinant protein ASCC1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
41 kDa
20 µg/$1,107
ASCC1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
41 kDa
100 µg/$494
ASCC1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
46 kDa
100 µg/$494
ASCC1 Protein
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E. coli
His
50 µg/$361; 250 µg/$739; 10 µg/$261
Viewing 1-7 of 7 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).