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ASAP1

ArfGAP with SH3 domain, ankyrin repeat and PH domain 1

Possesses phosphatidylinositol 4,5-bisphosphate-dependent GTPase-activating protein activity for ARF1 (ADP ribosylation factor 1) and ARF5 and a lesser activity towards ARF6. May coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2. May function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types (By similarity). Plays a role in ciliogenesis.

Gene Name: ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
Synonyms: ASAP1, AMAP1, Centaurin, beta 4, CENTB4, DEF-1, DDEF1, KIAA1249, PAP, PIP2-dependent ARF1 GAP, PAG2, ZG14P
Target Sequences: NM_018482 NP_060952.2 Q9ULH1

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Products
Antibodies (15)
Primary (15)
ASAP1 (15)
Human (9)
Mouse (11)
Rat (2)
Bovine (1)
Chicken (1)
Chimpanzee (1)
Dog (1)
IHC (2)
IHC-P (2)
WB (15)
ELISA (10)
IF (1)
IP (2)
Peptide-ELISA (1)
rabbit (14)
mouse (1)
Product Group
IHCPlus (2)
IgG (12)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (14)
1B5 (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (10)
aa360-388 (7)
C-Terminus (2)
aa700-750 (1)
aa750-800 (1)
aa962-978 (1)
No (15)
ASAP1 Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
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ASAP1 Mouse anti-Human Monoclonal (1B5) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
ASAP1 Antibody - Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
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ASAP1 Rabbit anti-Human Polyclonal (aa750-800) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$485
ASAP1 Antibody - Anti-ASAP1 Antibody - Immunofluorescent Microscopy. Immunofluorescent microscopy using Affinity Purified anti-ASAP1 antibody shows detection of ASAP1present in mouse NIH3T3 cells transfected with activated Src. Specific staining is not present when antibody is pre-incubated with the immunizing peptide prior to reaction with cells. Personal Communication. Paul Randazzo, NIH, CCR, Bethesda, MD.
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ASAP1 Rabbit anti-Mouse Polyclonal Antibody
Chicken, Bovine, Mouse, Dog, Rat, Chimpanzee, Human
ELISA, IF, WB
Unconjugated
100 µg/$567
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ASAP1 Rabbit anti-Human Polyclonal (aa360-388) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
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ASAP1 Rabbit anti-Mouse Polyclonal (aa360-388) (Biotin) Antibody
Mouse
ELISA, WB
Biotin Conjugated
200 µl/$952
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ASAP1 Rabbit anti-Mouse Polyclonal (aa360-388) (FITC) Antibody
Mouse
ELISA, WB
FITC Conjugated
200 µl/$952
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ASAP1 Rabbit anti-Mouse Polyclonal (aa360-388) (Azide-free) (HRP) Antibody
Mouse
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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ASAP1 Rabbit anti-Mouse Polyclonal (aa360-388) (PE) Antibody
Mouse
ELISA, WB
PE Conjugated
200 µl/$952
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ASAP1 Rabbit anti-Mouse Polyclonal (aa360-388) (APC) Antibody
Mouse
ELISA, WB
APC Conjugated
200 µl/$952
ASAP1 Antibody - Western Blot of rabbit anti-ASAP1 antibody. Lane 1: ASAP1 transfected lysate. Load: 35 µg per lane. Primary antibody: ASAP1 antibody at 1:1000 for overnight at 4°C. Secondary antibody: rabbit secondary HRP antibody at 1:70,000 for 30 min at RT. Block: BlockOut overnight at 4°C. Predicted/Observed size: 125 kda for ASAP1.
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ASAP1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$567
ASAP1 Antibody - Western Blot of rabbit anti-ASAP1 antibody. Lane 1: ASAP1 transfected lysate. Load: 35 µg per lane. Primary antibody: ASAP1 antibody at 1:1000 for overnight at 4°C. Secondary antibody: rabbit secondary HRP antibody at 1:70,000 for 30 min at RT. Block: BlockOut overnight at 4°C. Predicted/Observed size: 125 kda for ASAP1.
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ASAP1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, WB
Unconjugated
25 µl/$304
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ASAP1 Rabbit anti-Human Polyclonal (aa700-750) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
ASAP1 Antibody - Western blot analysis of ASAP1 using Jurkat whole cells lysates
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ASAP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ASAP1 Antibody - Western blot of ASAP1 in mouse brain lysate in the 1) absence and 2) presence of immunizing peptide using Polyclonal Antibody to ASAP1 at 2.0 ug/ml. Goat anti-rabbit Ig HRP secondary antibody, and PicoTect ECL substrate solution, were used for this test.
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ASAP1 Rabbit anti-Mouse Polyclonal (aa962-978) Antibody
Mouse
WB
Unconjugated
100 µg/$386
ASAP1 Antibody - ASAP1 Antibody western blot of mouse NIH-3T3 cell line lysates (35 ug/lane). The ASAP1 antibody detected the ASAP1 protein (arrow).
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ASAP1 Rabbit anti-Human Polyclonal (aa360-388) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
Viewing 1-15 of 15 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).