ASAH2

N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2

Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6.5-8.5. Acts as a key regulator of sphingolipid signaling metabolites by generating sphingosine at the cell surface. Acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine, a precursor of the antiapoptotic factor sphingosine 1-phosphate. Probably involved in the digestion of dietary sphingolipids in intestine by acting as a key enzyme for the catabolism of dietary sphingolipids and regulating the levels of bioactive sphingolipid metabolites in the intestinal tract.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

ASAH2 (3)

Publications

No (3)

Tag

His (1)

Myc-DDK (Flag) (2)

Species

Human (1)

Mouse (1)

Source

293T Cells (1)

HEK 293 Cells (1)

Human Cells (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (1)

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Human ASAH2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91175

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

83.1 kDa

Price:

20 µg/$215

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ASAH2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G111359

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

83.1 kDa

Price:

100 µg/$710

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Mouse ASAH2 Protein (Recombinant His) (Thr34-Thr756) - LS-G98702

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

82 kDa

Price:

50 µg/$854

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