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ASAH2

N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2

Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6.5-8.5. Acts as a key regulator of sphingolipid signaling metabolites by generating sphingosine at the cell surface. Acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine, a precursor of the antiapoptotic factor sphingosine 1-phosphate. Probably involved in the digestion of dietary sphingolipids in intestine by acting as a key enzyme for the catabolism of dietary sphingolipids and regulating the levels of bioactive sphingolipid metabolites in the intestinal tract.

Gene Name: N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
Synonyms: ASAH2, BCDase, Acylsphingosine deacylase 2, HCD, Mitochondrial ceramidase, NCDase, Non-lysosomal ceramidase, LCDase, N-CDase, Neutral ceramidase, HNAC1, Neutral/alkaline ceramidase
Target Sequences: NM_019893 NP_063946.2 Q9NR71

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Products
Antibodies (24)
Primary (24)
ASAH2 (24)
Human (19)
Mouse (20)
Rat (8)
IHC (5)
IHC-P (1)
WB (15)
ELISA (17)
rabbit (23)
sheep (1)
Product Group
IHCPlus (1)
IgG (18)
polyclonal pc (24)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (15)
aa734-762 (7)
aa34-756 (1)
No (24)
ASAH2 Antibody - Anti-ASAH2 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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ASAH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.05 mg/$545
ASAH2 Antibody - ASAH2 Antibody western blot of mouse bladder tissue lysates (35 ug/lane). The ASAH2 antibody detected the ASAH2 protein (arrow).
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ASAH2 Rabbit anti-Human Polyclonal (aa734-762) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
ASAH2 Antibody - Western blot analysis of Neutral Ceramidase expression in mouse kidney (A); mouse heart (B) whole cell lysates.
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ASAH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
ASAH2 Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer using ASAH2 Polyclonal Antibody at dilution of 1:40.
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ASAH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ASAH2 Antibody - Immunohistochemistry of paraffin-embedded Human brain using ASAH2 Polyclonal Antibody at dilution of 1:50.
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ASAH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ASAH2 Antibody - Immunohistochemistry of paraffin-embedded mouse brain tissue.
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ASAH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
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ASAH2 Rabbit anti-Human Polyclonal (aa734-762) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
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ASAH2 Rabbit anti-Human Polyclonal (aa734-762) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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ASAH2 Rabbit anti-Human Polyclonal (aa734-762) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
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ASAH2 Rabbit anti-Human Polyclonal (aa734-762) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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ASAH2 Rabbit anti-Human Polyclonal (aa734-762) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
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ASAH2 Rabbit anti-Human Polyclonal (aa734-762) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
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ASAH2 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
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ASAH2 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
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ASAH2 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
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ASAH2 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
ASAH2 Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue using ASAH2 Antibody at dilution of 1:100
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ASAH2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
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ASAH2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
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ASAH2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
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ASAH2 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
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ASAH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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ASAH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
ASAH2 Antibody - Western blot analysis of extracts of various cell lines, using ASAH2 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 1s.
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ASAH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
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ASAH2 Sheep anti-Mouse Polyclonal (aa34-756) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
50 µg/$973
Viewing 1-24 of 24 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).