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ASAH2

N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2

Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6.5-8.5. Acts as a key regulator of sphingolipid signaling metabolites by generating sphingosine at the cell surface. Acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine, a precursor of the antiapoptotic factor sphingosine 1-phosphate. Probably involved in the digestion of dietary sphingolipids in intestine by acting as a key enzyme for the catabolism of dietary sphingolipids and regulating the levels of bioactive sphingolipid metabolites in the intestinal tract.

Gene Name: N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
Synonyms: ASAH2, BCDase, Acylsphingosine deacylase 2, HCD, Mitochondrial ceramidase, NCDase, Non-lysosomal ceramidase, LCDase, N-CDase, Neutral ceramidase, HNAC1, Neutral/alkaline ceramidase
Target Sequences: NM_019893 NP_063946.2 Q9NR71

☰ Filters
Antibodies (24)
Proteins (3)
ELISA Kits (2)
Custom (1)
Over-Expression Lysate (2)
Primary (24)
Recombinant (1)
Sandwich (1)
ASAH2 (29)
Human (21)
Mouse (20)
Rat (8)
IHC (5)
IHC-P (1)
WB (15)
ELISA (17)
rabbit (23)
sheep (1)
Product Group
IHCPlus (1)
IgG (18)
polyclonal pc (24)
96-Well Microplate (1)
96-Well Strip Plate (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (15)
aa734-762 (7)
aa34-756 (1)
No (29)
Plasma (1)
Serum (1)
Tissue Homogenates (1)
His (1)
Myc-DDK (Flag) (2)
Human (1)
Mouse (1)
293T Cells (1)
HEK 293 Cells (1)
Human Cells (1)
Purified (1)
Low endotoxin level (1)
ASAH2 Antibody - Anti-ASAH2 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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ASAH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.05 mg/$545
ASAH2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
83.1 kDa
20 µg/$215
ASAH2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$730
ASAH2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
83.1 kDa
100 µg/$710
ASAH2 Antibody - ASAH2 Antibody western blot of mouse bladder tissue lysates (35 ug/lane). The ASAH2 antibody detected the ASAH2 protein (arrow).
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ASAH2 Rabbit anti-Human Polyclonal (aa734-762) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
ASAH2 Antibody - Western blot analysis of Neutral Ceramidase expression in mouse kidney (A); mouse heart (B) whole cell lysates.
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ASAH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
ASAH2 Antibody - Immunohistochemistry of paraffin-embedded Human brain using ASAH2 Polyclonal Antibody at dilution of 1:50.
Select
ASAH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ASAH2 Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer using ASAH2 Polyclonal Antibody at dilution of 1:40.
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ASAH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ASAH2 Antibody - Immunohistochemistry of paraffin-embedded mouse brain tissue.
Select
ASAH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
Select
ASAH2 Rabbit anti-Human Polyclonal (aa734-762) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
Select
ASAH2 Rabbit anti-Human Polyclonal (aa734-762) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
ASAH2 Rabbit anti-Human Polyclonal (aa734-762) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
ASAH2 Rabbit anti-Human Polyclonal (aa734-762) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
ASAH2 Rabbit anti-Human Polyclonal (aa734-762) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
ASAH2 Rabbit anti-Human Polyclonal (aa734-762) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
ASAH2 Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue using ASAH2 Antibody at dilution of 1:100
Select
ASAH2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
Select
ASAH2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
ASAH2 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
Select
ASAH2 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
Select
ASAH2 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
Select
ASAH2 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
Select
ASAH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Select
ASAH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
ASAH2 Antibody - Western blot analysis of extracts of various cell lines, using ASAH2 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 1s.
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ASAH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
Select
ASAH2 Sheep anti-Mouse Polyclonal (aa34-756) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
50 µg/$973
Viewing 1-25 of 29 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).