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Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
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ASAH1 / Acid Ceramidase
N-acylsphingosine amidohydrolase (acid ceramidase) 1
ASAH1 / Acid Ceramidase is a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into sphingosine and fatty acid. Mutations in this gene have been associated with a lysosomal storage disorder known as Farber disease. Multiple transcript variants encoding several distinct isoforms have been identified for this gene.
| Gene Name: | N-acylsphingosine amidohydrolase (acid ceramidase) 1 |
| Synonyms: | ASAH1, ACDase, Acid CDase, Acid ceramidase, ASAH, Acylsphingosine deacylase, PHP32, SMAPME, PHP, Putative 32 kDa heart protein |
| Target Sequences: | NM_004315 NP_004306.3 Q13510 |
Publications (1)
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