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ASAH1 / Acid Ceramidase

N-acylsphingosine amidohydrolase (acid ceramidase) 1

ASAH1 / Acid Ceramidase is a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into sphingosine and fatty acid. Mutations in this gene have been associated with a lysosomal storage disorder known as Farber disease. Multiple transcript variants encoding several distinct isoforms have been identified for this gene.

Gene Name: N-acylsphingosine amidohydrolase (acid ceramidase) 1
Synonyms: ASAH1, ACDase, Acid CDase, Acid ceramidase, ASAH, Acylsphingosine deacylase, PHP32, SMAPME, PHP, Putative 32 kDa heart protein
Target Sequences: NM_004315 NP_004306.3 Q13510

Publications (1)

1
Contribution of Hepatic Steatosis-Intensified Extracellular Vesicle Release to Aggravated Inflammatory Endothelial Injury in Liver-Specific Asah1 Gene Knockout Mice. Xinxu Yuan, Owais M Bhat, Yao Zou, Yang Zhang, Pin-Lan Li. The American journal of pathology. 2023 April;193:493-508. [Full Text Article] [PubMed:36638912] [PMC:PMC10123522] Related Antibodies: LS-B11969.

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Products
Antibodies (39)
Primary (39)
ASAH1 / Acid Ceramidase (39)
Human (38)
Mouse (17)
Rat (10)
Bat (3)
Bovine (6)
Chimpanzee (6)
Dog (6)
Gibbon (6)
Guinea pig (3)
Hamster (3)
Horse (3)
Monkey (7)
Orangutan (6)
IHC (20)
IHC-P (15)
WB (35)
ELISA (13)
IF (2)
IP (1)
Peptide-ELISA (1)
rabbit (37)
mouse (2)
Product Group
IHCPlus (4)
IgG (24)
IgG3,k (2)
monoclonal mc (2)
polyclonal pc (37)
1A7 (1)
2C9 (1)
APC (1)
APC Conjugated (2)
Biotin Conjugated (5)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (2)
Unconjugated (18)
aa143-395 (8)
N-Terminus (4)
aa287-336 (4)
aa146-395 (2)
No (38)
Yes (1)
ASAH1 / Acid Ceramidase Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
ASAH1 / Acid Ceramidase Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
ASAH1 / Acid Ceramidase Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
ASAH1 / Acid Ceramidase Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
ASAH1 / Acid Ceramidase Antibody - Anti-ASAH1 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
ASAH1 / Acid Ceramidase Antibody - Anti-ASAH1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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ASAH1 / Acid Ceramidase Mouse anti-Human Monoclonal (1A7) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$440
ASAH1 / Acid Ceramidase Antibody - Immunohistochemistry of paraffin-embedded human heart using antibody at 1:100 dilution.
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ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal (aa146-395) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
ASAH1 / Acid Ceramidase Antibody - Immunoperoxidase of monoclonal antibody to ASAH1 on formalin-fixed paraffin-embedded human heart (antibody concentration 3 ug/ml).
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ASAH1 / Acid Ceramidase Mouse anti-Human Monoclonal (2C9) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$423
ASAH1 / Acid Ceramidase Antibody - Immunohistochemistry of paraffin-embedded Human cervical cancer using ASAH1 Polyclonal Antibody at dilution of 1:40.
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ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
ASAH1 / Acid Ceramidase Antibody - Western blot of ASAH1 / Acid Ceramidase antibody.
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ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal (aa143-395) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
ASAH1 / Acid Ceramidase Antibody - Western blot analysis of extracts of various cell lines.
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ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
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ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$341
ASAH1 / Acid Ceramidase Antibody - Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal (aa287-336) Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
ASAH1 / Acid Ceramidase Antibody - Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal (aa287-336) (HRP) Antibody
Dog, Bovine, Human, Monkey, Chimpanzee, Orangutan, Gibbon
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
ASAH1 / Acid Ceramidase Antibody - Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal (aa287-336) (Biotin) Antibody
Dog, Bovine, Human, Monkey, Chimpanzee, Orangutan, Gibbon
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
ASAH1 / Acid Ceramidase Antibody - Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal (aa287-336) (FITC) Antibody
Dog, Bovine, Human, Monkey, Chimpanzee, Orangutan, Gibbon
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
Select
ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$475
ASAH1 / Acid Ceramidase Antibody - Immunohistochemistry of paraffin-embedded human heart tissue at dilution of 1:100
Select
ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
ASAH1 / Acid Ceramidase Antibody - Immunohistochemistry of paraffin-embedded Human cervical cancer using ASAH1 Polyclonal Antibody at dilution of 1:50.
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ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ASAH1 / Acid Ceramidase Antibody - Immunohistochemistry of paraffin-embedded human heart using antibody at 1:100 dilution.
Select
ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal (aa146-395) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
ASAH1 / Acid Ceramidase Antibody - 1:100 staining human lymph carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ASAH1 / Acid Ceramidase Antibody - Western blot analysis of Acid Ceramidase expression in mouse kidney (A); rat heart (B) whole cell lysates.
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ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
ASAH1 / Acid Ceramidase Antibody - Western blot analysis of extracts of various cell lines, using ASAH1 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
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ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).