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ASAH1 / Acid Ceramidase
N-acylsphingosine amidohydrolase (acid ceramidase) 1
ASAH1 / Acid Ceramidase is a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into sphingosine and fatty acid. Mutations in this gene have been associated with a lysosomal storage disorder known as Farber disease. Multiple transcript variants encoding several distinct isoforms have been identified for this gene.
| Gene Name: | N-acylsphingosine amidohydrolase (acid ceramidase) 1 |
| Synonyms: | ASAH1, ACDase, Acid CDase, Acid ceramidase, ASAH, Acylsphingosine deacylase, PHP32, SMAPME, PHP, Putative 32 kDa heart protein |
| Target Sequences: | NM_004315 NP_004306.3 Q13510 |
Publications (1)
1
Contribution of Hepatic Steatosis-Intensified Extracellular Vesicle Release to Aggravated Inflammatory Endothelial Injury in Liver-Specific Asah1 Gene Knockout Mice. Xinxu Yuan, Owais M Bhat, Yao Zou, Yang Zhang, Pin-Lan Li. The American journal of pathology. 2023 April;193:493-508. [Full Text Article]
[PubMed:36638912]
[PMC:PMC10123522]
Related Antibodies: LS-B11969.
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ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
ASAH1 / Acid Ceramidase Mouse anti-Human Monoclonal (1A7) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$440
ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal (aa146-395) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
ASAH1 / Acid Ceramidase Mouse anti-Human Monoclonal (2C9) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$423
ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$730
E. coli
His
32.7 kDa
10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal (aa143-395) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
E. coli
6His-SUMO, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$341
ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal (aa287-336) Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal (aa287-336) (Biotin) Antibody
Dog, Bovine, Human, Monkey, Chimpanzee, Orangutan, Gibbon
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal (aa287-336) (FITC) Antibody
Dog, Bovine, Human, Monkey, Chimpanzee, Orangutan, Gibbon
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$475
Wheat Germ Extract
GST
71 kDa
2 µg/$439
ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
E. coli
10His-SUMO, N-terminus + Myc, C-terminus
100 µg/$1,128; 20 µg/$721
ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ASAH1 / Acid Ceramidase Rabbit anti-Human Polyclonal (aa146-395) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
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