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ARX is a homeobox-containing gene expressed during development. The expressed protein contains two conserved domains, a C-peptide (or aristaless domain) and the prd-like class homeobox domain. It is a member of the group-II aristaless-related protein family whose members are expressed primarily in the central and/or peripheral nervous system. This gene is thought to be involved in CNS development. Mutations in this gene cause X-linked mental retardation and epilepsy.
Gene Name: | aristaless related homeobox |
Synonyms: | ARX, Aristaless-related homeobox, Aristaless related homeobox, Cancer/testis antigen 121, EIEE1, MRX29, MRX33, MRX38, MRX54, MRX32, MRX76, MRXS1, ISSX, MRX43, PRTS, CT121, Homeobox protein ARX, MRX36, MRX87 |
Target Sequences: | Q96QS3 Q96QS3 |
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