ARVCF

armadillo repeat gene deleted in velocardiofacial syndrome

Armadillo Repeat gene deleted in Velo-Cardio-Facial syndrome (ARVCF) is a member of the catenin family. This family plays an important role in the formation of adherens junction complexes, which are thought to facilitate communication between the inside and outside environments of a cell. The ARVCF gene was isolated in the search for the genetic defect responsible for the autosomal dominant Velo-Cardio-Facial syndrome (VCFS), a relatively common human disorder with phenotypic features including cleft palate, conotruncal heart defects and facial dysmorphology. The ARVCF gene encodes a protein containing two motifs, a coiled coil domain in the N-terminus and a 10 armadillo repeat sequence in the midregion. Since these sequences can facilitate protein-protein interactions ARVCF is thought to function in a protein complex. In addition, ARVCF contains a predicted nuclear-targeting sequence suggesting that it may have a function as a nuclear protein.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

ARVCF (3)

Publications

No (3)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

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Human ARVCF Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81625

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

104.6 kDa

Price:

20 µg/$215

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Human ARVCF Protein (Recombinant GST, N-terminus) (aa863-962) - LS-G57824

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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ARVCF Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118444

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

104.6 kDa

Price:

100 µg/$710

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